Ensemble-based screening of natural products and FDA-approved drugs identified potent inhibitors of SARS-CoV-2 that work with two distinct mechanisms

The recent outbreak of SARS-CoV-2 is responsible for high morbidity and mortality rate across the globe. This requires an urgent identification of drugs and other interventions to overcome this pandemic. Computational drug repurposing represents an alternative approach to provide a more effective ap...

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Detalles Bibliográficos
Autores principales: Shadrack, Daniel M., Deogratias, Geradius, Kiruri, Lucy W., Swai, Hulda S., Vianney, John-Mary, Nyandoro, Stephen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901283/
https://www.ncbi.nlm.nih.gov/pubmed/33684603
http://dx.doi.org/10.1016/j.jmgm.2021.107871

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