High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways

Macrophages are critical effector cells of the immune system, and understanding genes involved in their viability and function is essential for gaining insights into immune system dysregulation during disease. We use a high-throughput, pooled-based CRISPR-Cas screening approach to identify essential...

Descripción completa

Detalles Bibliográficos
Autores principales: Covarrubias, Sergio, Cortez Vollmers, Apple, Capili, Allyson, Boettcher, Michael, Shulkin, Aaron, Correa, Michele Ramos, Halasz, Haley, Robinson, Elektra K., O’Briain, Laura, Vollmers, Christopher, Blau, James, Katzman, Sol, McManus, Michael T., Carpenter, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901356/
https://www.ncbi.nlm.nih.gov/pubmed/33378675
http://dx.doi.org/10.1016/j.celrep.2020.108541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901356/
https://www.ncbi.nlm.nih.gov/pubmed/33378675
http://dx.doi.org/10.1016/j.celrep.2020.108541

Ejemplares similares