Full Activation of Kinase Protein Kinase B by Phosphoinositide-Dependent Protein Kinase-1 and Mammalian Target of Rapamycin Complex 2 Is Required for Early Natural Killer Cell Development and Survival

The role of PI3K-mTOR pathway in regulating NK cell development has been widely reported. However, it remains unclear whether NK cell development depends on the protein kinase B (PKB), which links PI3K and mTOR, perhaps due to the potential redundancy of PKB. PKB has two phosphorylation sites, threo...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Junming, Zhao, Jun, Quan, Yuhe, Hou, Xinlei, Yang, Meixiang, Dong, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901528/
https://www.ncbi.nlm.nih.gov/pubmed/33633735
http://dx.doi.org/10.3389/fimmu.2020.617404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901528/
https://www.ncbi.nlm.nih.gov/pubmed/33633735
http://dx.doi.org/10.3389/fimmu.2020.617404

Ejemplares similares