Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor

[Image: see text] Pregnane X receptor (PXR) is a master xenobiotic-sensing transcription factor and a validated target for immune and inflammatory diseases. The identification of chemical probes to investigate the therapeutic relevance of the receptor is still highly desired. In fact, currently avai...

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Detalles Bibliográficos
Autores principales: Bartolini, Desirée, De Franco, Francesca, Torquato, Pierangelo, Marinelli, Rita, Cerra, Bruno, Ronchetti, Riccardo, Schon, Arne, Fallarino, Francesca, De Luca, Antonella, Bellezza, Guido, Ferri, Ivana, Sidoni, Angelo, Walton, William G., Pellock, Samuel J., Redinbo, Matthew R., Mani, Sridhar, Pellicciari, Roberto, Gioiello, Antimo, Galli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901650/
https://www.ncbi.nlm.nih.gov/pubmed/32160459
http://dx.doi.org/10.1021/acs.jmedchem.0c00012

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