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Total Synthesis of ent-Plagiochianin B
[Image: see text] An enantioselective total synthesis of plagiochianin B is described that employs (+)-3-carene as its point of departure and delivers the enantiomer of the natural product. Key features of the synthesis include a palladium-mediated regioselective oxidative cleavage of an olefin resi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901668/ https://www.ncbi.nlm.nih.gov/pubmed/33517659 http://dx.doi.org/10.1021/acs.orglett.0c04219 |
| _version_ | 1783654406811549696 |
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| author | Jackson, Richard K. Wood, John L. |
| author_facet | Jackson, Richard K. Wood, John L. |
| author_sort | Jackson, Richard K. |
| collection | PubMed |
| description | [Image: see text] An enantioselective total synthesis of plagiochianin B is described that employs (+)-3-carene as its point of departure and delivers the enantiomer of the natural product. Key features of the synthesis include a palladium-mediated regioselective oxidative cleavage of an olefin residing on a pyridine derived from a 6π-azatriene electrocyclization. |
| format | Online Article Text |
| id | pubmed-7901668 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | American Chemical Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-79016682021-02-24 Total Synthesis of ent-Plagiochianin B Jackson, Richard K. Wood, John L. Org Lett [Image: see text] An enantioselective total synthesis of plagiochianin B is described that employs (+)-3-carene as its point of departure and delivers the enantiomer of the natural product. Key features of the synthesis include a palladium-mediated regioselective oxidative cleavage of an olefin residing on a pyridine derived from a 6π-azatriene electrocyclization. American Chemical Society 2021-01-30 2021-02-19 /pmc/articles/PMC7901668/ /pubmed/33517659 http://dx.doi.org/10.1021/acs.orglett.0c04219 Text en © 2021 American Chemical Society Made available through a Creative Commons CC-BY-NC-ND License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) |
| spellingShingle | Jackson, Richard K. Wood, John L. Total Synthesis of ent-Plagiochianin B |
| title | Total Synthesis of ent-Plagiochianin B |
| title_full | Total Synthesis of ent-Plagiochianin B |
| title_fullStr | Total Synthesis of ent-Plagiochianin B |
| title_full_unstemmed | Total Synthesis of ent-Plagiochianin B |
| title_short | Total Synthesis of ent-Plagiochianin B |
| title_sort | total synthesis of ent-plagiochianin b |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901668/ https://www.ncbi.nlm.nih.gov/pubmed/33517659 http://dx.doi.org/10.1021/acs.orglett.0c04219 |
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