Cargando…
The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults–A cross sectional study
Population specific associations between cardiovascular disease with various risk factors including pre-hypertension and hypertension were reported. We aimed to investigate the association of higher than optimal blood pressure with measures of dysglycemia, dyslipidemia, and markers of inflammation i...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901777/ https://www.ncbi.nlm.nih.gov/pubmed/33621259 http://dx.doi.org/10.1371/journal.pone.0246568 |
_version_ | 1783654428628221952 |
---|---|
author | Ajabnoor, Ghada M. A. Bahijri, Suhad Alamoudi, Aliaa Amr Al Raddadi, Rajaa Al-Ahmadi, Jawaher Jambi, Hanan Borai, Anwar Toumilehto, Jaakko |
author_facet | Ajabnoor, Ghada M. A. Bahijri, Suhad Alamoudi, Aliaa Amr Al Raddadi, Rajaa Al-Ahmadi, Jawaher Jambi, Hanan Borai, Anwar Toumilehto, Jaakko |
author_sort | Ajabnoor, Ghada M. A. |
collection | PubMed |
description | Population specific associations between cardiovascular disease with various risk factors including pre-hypertension and hypertension were reported. We aimed to investigate the association of higher than optimal blood pressure with measures of dysglycemia, dyslipidemia, and markers of inflammation in non-diabetic Saudi adults hoping to improve current Saudi guidelines to prevent cardiovascular disease. Volunteers were recruited randomly from public healthcare centers in Jeddah. Demographic information, blood pressure (BP), and anthropometric measurements were taken. Fasting blood samples were drawn, then again following 1-hour oral glucose tolerance test. Glycated hemoglobin, fasting plasma glucose (FPG), lipid profile, highly sensitive C- reactive protein, gamma glutamyl transferase, and 1-hour plasma glucose were measured. Complete data was found for 742 men and 592 women. Pre-hypertension was found in 47.2% of men, and 24.7% of women, while 15.1% of men, and 14.6% of women were hypertensive. Means of measured variables differed significantly between normotensive, pre-hypertensive, and hypertensive groups of men and women in gender specific manner. Association between measured variables and elevated BP, and hypertension were assessed using logistic regression models. After adjustment for age, body mass index and waist circumference, elevated blood pressure was associated with elevated triglycerides in men, while hypertension was significantly associated with elevated fasting plasma glucose, total cholesterol, triglycerides, low density lipoprotein- cholesterol, and low high density lipoprotein- cholesterol in men, and elevated triglycerides, and total cholesterol in women. Therefore, it is strongly recommended to measure lipid profile, specifically TG, for all diagnosed pre-hypertensive and hypertensive patients in addition to FPG for men. |
format | Online Article Text |
id | pubmed-7901777 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-79017772021-03-02 The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults–A cross sectional study Ajabnoor, Ghada M. A. Bahijri, Suhad Alamoudi, Aliaa Amr Al Raddadi, Rajaa Al-Ahmadi, Jawaher Jambi, Hanan Borai, Anwar Toumilehto, Jaakko PLoS One Research Article Population specific associations between cardiovascular disease with various risk factors including pre-hypertension and hypertension were reported. We aimed to investigate the association of higher than optimal blood pressure with measures of dysglycemia, dyslipidemia, and markers of inflammation in non-diabetic Saudi adults hoping to improve current Saudi guidelines to prevent cardiovascular disease. Volunteers were recruited randomly from public healthcare centers in Jeddah. Demographic information, blood pressure (BP), and anthropometric measurements were taken. Fasting blood samples were drawn, then again following 1-hour oral glucose tolerance test. Glycated hemoglobin, fasting plasma glucose (FPG), lipid profile, highly sensitive C- reactive protein, gamma glutamyl transferase, and 1-hour plasma glucose were measured. Complete data was found for 742 men and 592 women. Pre-hypertension was found in 47.2% of men, and 24.7% of women, while 15.1% of men, and 14.6% of women were hypertensive. Means of measured variables differed significantly between normotensive, pre-hypertensive, and hypertensive groups of men and women in gender specific manner. Association between measured variables and elevated BP, and hypertension were assessed using logistic regression models. After adjustment for age, body mass index and waist circumference, elevated blood pressure was associated with elevated triglycerides in men, while hypertension was significantly associated with elevated fasting plasma glucose, total cholesterol, triglycerides, low density lipoprotein- cholesterol, and low high density lipoprotein- cholesterol in men, and elevated triglycerides, and total cholesterol in women. Therefore, it is strongly recommended to measure lipid profile, specifically TG, for all diagnosed pre-hypertensive and hypertensive patients in addition to FPG for men. Public Library of Science 2021-02-23 /pmc/articles/PMC7901777/ /pubmed/33621259 http://dx.doi.org/10.1371/journal.pone.0246568 Text en © 2021 Ajabnoor et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Ajabnoor, Ghada M. A. Bahijri, Suhad Alamoudi, Aliaa Amr Al Raddadi, Rajaa Al-Ahmadi, Jawaher Jambi, Hanan Borai, Anwar Toumilehto, Jaakko The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults–A cross sectional study |
title | The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults–A cross sectional study |
title_full | The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults–A cross sectional study |
title_fullStr | The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults–A cross sectional study |
title_full_unstemmed | The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults–A cross sectional study |
title_short | The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults–A cross sectional study |
title_sort | association between hypertension and other cardiovascular risk factors among non-diabetic saudis adults–a cross sectional study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901777/ https://www.ncbi.nlm.nih.gov/pubmed/33621259 http://dx.doi.org/10.1371/journal.pone.0246568 |
work_keys_str_mv | AT ajabnoorghadama theassociationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT bahijrisuhad theassociationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT alamoudialiaaamr theassociationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT alraddadirajaa theassociationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT alahmadijawaher theassociationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT jambihanan theassociationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT boraianwar theassociationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT toumilehtojaakko theassociationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT ajabnoorghadama associationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT bahijrisuhad associationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT alamoudialiaaamr associationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT alraddadirajaa associationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT alahmadijawaher associationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT jambihanan associationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT boraianwar associationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy AT toumilehtojaakko associationbetweenhypertensionandothercardiovascularriskfactorsamongnondiabeticsaudisadultsacrosssectionalstudy |