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Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction

Metabolic reprogramming between resistance and tolerance occurs within the immune system in response to sepsis. While metabolic tissues such as the liver are subjected to damage during sepsis, how their metabolic and energy reprogramming ensures survival is unclear. Employing comprehensive metabolom...

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Detalles Bibliográficos
Autores principales: Mainali, Rabina, Zabalawi, Manal, Long, David, Buechler, Nancy, Quillen, Ellen, Key, Chia-Chi, Zhu, Xuewei, Parks, John S, Furdui, Cristina, Stacpoole, Peter W, Martinez, Jennifer, McCall, Charles E, Quinn, Matthew A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901874/
https://www.ncbi.nlm.nih.gov/pubmed/33616039
http://dx.doi.org/10.7554/eLife.64611