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Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction
Metabolic reprogramming between resistance and tolerance occurs within the immune system in response to sepsis. While metabolic tissues such as the liver are subjected to damage during sepsis, how their metabolic and energy reprogramming ensures survival is unclear. Employing comprehensive metabolom...
Autores principales: | Mainali, Rabina, Zabalawi, Manal, Long, David, Buechler, Nancy, Quillen, Ellen, Key, Chia-Chi, Zhu, Xuewei, Parks, John S, Furdui, Cristina, Stacpoole, Peter W, Martinez, Jennifer, McCall, Charles E, Quinn, Matthew A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901874/ https://www.ncbi.nlm.nih.gov/pubmed/33616039 http://dx.doi.org/10.7554/eLife.64611 |
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