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FoxO1 Is a Novel Regulator of 20S Proteasome Subunits Expression and Activity

Proteostasis collapses during aging resulting, among other things, in the accumulation of damaged and aggregated proteins. The proteasome is the main cellular proteolytic system and plays a fundamental role in the maintenance of protein homeostasis. Our previous work has demonstrated that senescence...

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Detalles Bibliográficos
Autores principales: Kapetanou, Marianna, Nespital, Tobias, Tain, Luke S., Pahl, Andre, Partridge, Linda, Gonos, Efstathios S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901890/
https://www.ncbi.nlm.nih.gov/pubmed/33634126
http://dx.doi.org/10.3389/fcell.2021.625715

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