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FoxO1 Is a Novel Regulator of 20S Proteasome Subunits Expression and Activity
Proteostasis collapses during aging resulting, among other things, in the accumulation of damaged and aggregated proteins. The proteasome is the main cellular proteolytic system and plays a fundamental role in the maintenance of protein homeostasis. Our previous work has demonstrated that senescence...
Autores principales: | Kapetanou, Marianna, Nespital, Tobias, Tain, Luke S., Pahl, Andre, Partridge, Linda, Gonos, Efstathios S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901890/ https://www.ncbi.nlm.nih.gov/pubmed/33634126 http://dx.doi.org/10.3389/fcell.2021.625715 |
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