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Unilateral Nephrectomy Stimulates ERK and Is Associated With Enhanced Na Transport
Nephron loss initiates compensatory hemodynamic and cellular effects on the remaining nephrons. Increases in single nephron glomerular filtration rate and tubular flow rate exert higher fluid shear stress (FSS) on tubules. In principal cell (PC) culture models FSS induces ERK, and ERK is implicated...
Autores principales: | Repetti, Robert, Majumder, Nomrota, De Oliveira, Karin Carneiro, Meth, Jennifer, Yangchen, Tenzin, Sharma, Mukut, Srivastava, Tarak, Rohatgi, Rajeev |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901926/ https://www.ncbi.nlm.nih.gov/pubmed/33633581 http://dx.doi.org/10.3389/fphys.2021.583453 |
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