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Activation of Prefrontal Cortex in Process of Oral and Finger Shape Discrimination: fNIRS Study

BACKGROUND: The differences in the brain activities of the insular and the visual association cortices have been reported between oral and manual stereognosis. However, these results were not conclusive because of the inherent differences in the task performance-related motor sequence conditions. We...

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Autores principales: Narita, Noriyuki, Kamiya, Kazunobu, Iwaki, Sunao, Ishii, Tomohiro, Endo, Hiroshi, Shimosaka, Michiharu, Uchida, Takeshi, Kantake, Ikuo, Shibutani, Koh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901927/
https://www.ncbi.nlm.nih.gov/pubmed/33633532
http://dx.doi.org/10.3389/fnins.2021.588593
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author Narita, Noriyuki
Kamiya, Kazunobu
Iwaki, Sunao
Ishii, Tomohiro
Endo, Hiroshi
Shimosaka, Michiharu
Uchida, Takeshi
Kantake, Ikuo
Shibutani, Koh
author_facet Narita, Noriyuki
Kamiya, Kazunobu
Iwaki, Sunao
Ishii, Tomohiro
Endo, Hiroshi
Shimosaka, Michiharu
Uchida, Takeshi
Kantake, Ikuo
Shibutani, Koh
author_sort Narita, Noriyuki
collection PubMed
description BACKGROUND: The differences in the brain activities of the insular and the visual association cortices have been reported between oral and manual stereognosis. However, these results were not conclusive because of the inherent differences in the task performance-related motor sequence conditions. We hypothesized that the involvement of the prefrontal cortex may be different between finger and oral shape discrimination. This study was conducted to clarify temporal changes in prefrontal activities occurring in the processes of oral and finger tactual shape discrimination using prefrontal functional near-infrared spectroscopy (fNIRS). METHODS: Six healthy right-handed males [aged 30.8 ± 8.2 years (mean ± SD)] were enrolled. Measurements of prefrontal activities were performed using a 22-channel fNIRS device (ETG-100, Hitachi Medical Co., Chiba, Japan) during experimental blocks that included resting state (REST), nonsense shape discrimination (SHAM), and shape discrimination (SHAPE). RESULTS: No significant difference was presented with regard to the number of correct answers during trials between oral and finger SHAPE discrimination. Additionally, a statistical difference for the prefrontal fNIRS activity between oral and finger shape discrimination was noted in CH 1. Finger SHAPE, as compared with SHAM, presented a temporally shifting onset and burst in the prefrontal activities from the frontopolar area (FPA) to the orbitofrontal cortex (OFC). In contrast, oral SHAPE as compared with SHAM was shown to be temporally overlapped in the onset and burst of the prefrontal activities in the dorsolateral prefrontal cortex (DLPFC)/FPA/OFC. CONCLUSION: The prefrontal activities temporally shifting from the FPA to the OFC during SHAPE as compared with SHAM may suggest the segregated serial prefrontal processing from the manipulation of a target image to the decision making during the process of finger shape discrimination. In contrast, the temporally overlapped prefrontal activities of the DLPFC/FPA/OFC in the oral SHAPE block may suggest the parallel procession of the repetitive involvement of generation, manipulation, and decision making in order to form a reliable representation of target objects.
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spelling pubmed-79019272021-02-24 Activation of Prefrontal Cortex in Process of Oral and Finger Shape Discrimination: fNIRS Study Narita, Noriyuki Kamiya, Kazunobu Iwaki, Sunao Ishii, Tomohiro Endo, Hiroshi Shimosaka, Michiharu Uchida, Takeshi Kantake, Ikuo Shibutani, Koh Front Neurosci Neuroscience BACKGROUND: The differences in the brain activities of the insular and the visual association cortices have been reported between oral and manual stereognosis. However, these results were not conclusive because of the inherent differences in the task performance-related motor sequence conditions. We hypothesized that the involvement of the prefrontal cortex may be different between finger and oral shape discrimination. This study was conducted to clarify temporal changes in prefrontal activities occurring in the processes of oral and finger tactual shape discrimination using prefrontal functional near-infrared spectroscopy (fNIRS). METHODS: Six healthy right-handed males [aged 30.8 ± 8.2 years (mean ± SD)] were enrolled. Measurements of prefrontal activities were performed using a 22-channel fNIRS device (ETG-100, Hitachi Medical Co., Chiba, Japan) during experimental blocks that included resting state (REST), nonsense shape discrimination (SHAM), and shape discrimination (SHAPE). RESULTS: No significant difference was presented with regard to the number of correct answers during trials between oral and finger SHAPE discrimination. Additionally, a statistical difference for the prefrontal fNIRS activity between oral and finger shape discrimination was noted in CH 1. Finger SHAPE, as compared with SHAM, presented a temporally shifting onset and burst in the prefrontal activities from the frontopolar area (FPA) to the orbitofrontal cortex (OFC). In contrast, oral SHAPE as compared with SHAM was shown to be temporally overlapped in the onset and burst of the prefrontal activities in the dorsolateral prefrontal cortex (DLPFC)/FPA/OFC. CONCLUSION: The prefrontal activities temporally shifting from the FPA to the OFC during SHAPE as compared with SHAM may suggest the segregated serial prefrontal processing from the manipulation of a target image to the decision making during the process of finger shape discrimination. In contrast, the temporally overlapped prefrontal activities of the DLPFC/FPA/OFC in the oral SHAPE block may suggest the parallel procession of the repetitive involvement of generation, manipulation, and decision making in order to form a reliable representation of target objects. Frontiers Media S.A. 2021-02-05 /pmc/articles/PMC7901927/ /pubmed/33633532 http://dx.doi.org/10.3389/fnins.2021.588593 Text en Copyright © 2021 Narita, Kamiya, Iwaki, Ishii, Endo, Shimosaka, Uchida, Kantake and Shibutani. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Narita, Noriyuki
Kamiya, Kazunobu
Iwaki, Sunao
Ishii, Tomohiro
Endo, Hiroshi
Shimosaka, Michiharu
Uchida, Takeshi
Kantake, Ikuo
Shibutani, Koh
Activation of Prefrontal Cortex in Process of Oral and Finger Shape Discrimination: fNIRS Study
title Activation of Prefrontal Cortex in Process of Oral and Finger Shape Discrimination: fNIRS Study
title_full Activation of Prefrontal Cortex in Process of Oral and Finger Shape Discrimination: fNIRS Study
title_fullStr Activation of Prefrontal Cortex in Process of Oral and Finger Shape Discrimination: fNIRS Study
title_full_unstemmed Activation of Prefrontal Cortex in Process of Oral and Finger Shape Discrimination: fNIRS Study
title_short Activation of Prefrontal Cortex in Process of Oral and Finger Shape Discrimination: fNIRS Study
title_sort activation of prefrontal cortex in process of oral and finger shape discrimination: fnirs study
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901927/
https://www.ncbi.nlm.nih.gov/pubmed/33633532
http://dx.doi.org/10.3389/fnins.2021.588593
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