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Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates

Fluvastatin (FLV) is a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor often used to lower total and low-density lipoprotein (LDL) cholesterol and for the prevention of adverse cardiovascular events. This drug as well as melittin (MEL), the major component of honeybee venom (Apis mell...

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Detalles Bibliográficos
Autores principales: Badr-Eldin, Shaimaa M., Alhakamy, Nabil A., Fahmy, Usama A., Ahmed, Osama A. A., Asfour, Hani Z., Althagafi, Abdulhamid A., Aldawsari, Hibah M., Rizg, Waleed Y., Mahdi, Wael A., Alghaith, Adel F., Alshehri, Sultan, Caraci, Filippo, Caruso, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901935/
https://www.ncbi.nlm.nih.gov/pubmed/33633571
http://dx.doi.org/10.3389/fphar.2020.642171

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