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Exhausted CD8+T Cells in the Tumor Immune Microenvironment: New Pathways to Therapy

Tumor-specific CD8(+)T cells are exposed to persistent antigenic stimulation which induces a dysfunctional state called “exhaustion.” Though functioning to limit damage caused by immune response, T cell exhaustion leads to attenuated effector function whereby cytotoxic CD8(+)T cells fail to control...

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Detalles Bibliográficos
Autores principales:	Jiang, Weiqin, He, Yinjun, He, Wenguang, Wu, Guosheng, Zhou, Xile, Sheng, Qinsong, Zhong, Weixiang, Lu, Yimin, Ding, Yongfeng, Lu, Qi, Ye, Feng, Hua, Hanju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902023/ https://www.ncbi.nlm.nih.gov/pubmed/33633741 http://dx.doi.org/10.3389/fimmu.2020.622509

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