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Evolution of Protein-Mediated Biomineralization in Scleractinian Corals

While recent strides have been made in understanding the biological process by which stony corals calcify, much remains to be revealed, including the ubiquity across taxa of specific biomolecules involved. Several proteins associated with this process have been identified through proteomic profiling...

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Autores principales: Zaquin, Tal, Malik, Assaf, Drake, Jeana L., Putnam, Hollie M., Mass, Tali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902050/
https://www.ncbi.nlm.nih.gov/pubmed/33633782
http://dx.doi.org/10.3389/fgene.2021.618517
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author Zaquin, Tal
Malik, Assaf
Drake, Jeana L.
Putnam, Hollie M.
Mass, Tali
author_facet Zaquin, Tal
Malik, Assaf
Drake, Jeana L.
Putnam, Hollie M.
Mass, Tali
author_sort Zaquin, Tal
collection PubMed
description While recent strides have been made in understanding the biological process by which stony corals calcify, much remains to be revealed, including the ubiquity across taxa of specific biomolecules involved. Several proteins associated with this process have been identified through proteomic profiling of the skeletal organic matrix (SOM) extracted from three scleractinian species. However, the evolutionary history of this putative “biomineralization toolkit,” including the appearance of these proteins’ throughout metazoan evolution, remains to be resolved. Here we used a phylogenetic approach to examine the evolution of the known scleractinians’ SOM proteins across the Metazoa. Our analysis reveals an evolutionary process dominated by the co-option of genes that originated before the cnidarian diversification. Each one of the three species appears to express a unique set of the more ancient genes, representing the independent co-option of SOM proteins, as well as a substantial proportion of proteins that evolved independently. In addition, in some instances, the different species expressed multiple orthologous proteins sharing the same evolutionary history. Furthermore, the non-random clustering of multiple SOM proteins within scleractinian-specific branches suggests the conservation of protein function between distinct species for what we posit is part of the scleractinian “core biomineralization toolkit.” This “core set” contains proteins that are likely fundamental to the scleractinian biomineralization mechanism. From this analysis, we infer that the scleractinians’ ability to calcify was achieved primarily through multiple lineage-specific protein expansions, which resulted in a new functional role that was not present in the parent gene.
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spelling pubmed-79020502021-02-24 Evolution of Protein-Mediated Biomineralization in Scleractinian Corals Zaquin, Tal Malik, Assaf Drake, Jeana L. Putnam, Hollie M. Mass, Tali Front Genet Genetics While recent strides have been made in understanding the biological process by which stony corals calcify, much remains to be revealed, including the ubiquity across taxa of specific biomolecules involved. Several proteins associated with this process have been identified through proteomic profiling of the skeletal organic matrix (SOM) extracted from three scleractinian species. However, the evolutionary history of this putative “biomineralization toolkit,” including the appearance of these proteins’ throughout metazoan evolution, remains to be resolved. Here we used a phylogenetic approach to examine the evolution of the known scleractinians’ SOM proteins across the Metazoa. Our analysis reveals an evolutionary process dominated by the co-option of genes that originated before the cnidarian diversification. Each one of the three species appears to express a unique set of the more ancient genes, representing the independent co-option of SOM proteins, as well as a substantial proportion of proteins that evolved independently. In addition, in some instances, the different species expressed multiple orthologous proteins sharing the same evolutionary history. Furthermore, the non-random clustering of multiple SOM proteins within scleractinian-specific branches suggests the conservation of protein function between distinct species for what we posit is part of the scleractinian “core biomineralization toolkit.” This “core set” contains proteins that are likely fundamental to the scleractinian biomineralization mechanism. From this analysis, we infer that the scleractinians’ ability to calcify was achieved primarily through multiple lineage-specific protein expansions, which resulted in a new functional role that was not present in the parent gene. Frontiers Media S.A. 2021-02-02 /pmc/articles/PMC7902050/ /pubmed/33633782 http://dx.doi.org/10.3389/fgene.2021.618517 Text en Copyright © 2021 Zaquin, Malik, Drake, Putnam and Mass. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Zaquin, Tal
Malik, Assaf
Drake, Jeana L.
Putnam, Hollie M.
Mass, Tali
Evolution of Protein-Mediated Biomineralization in Scleractinian Corals
title Evolution of Protein-Mediated Biomineralization in Scleractinian Corals
title_full Evolution of Protein-Mediated Biomineralization in Scleractinian Corals
title_fullStr Evolution of Protein-Mediated Biomineralization in Scleractinian Corals
title_full_unstemmed Evolution of Protein-Mediated Biomineralization in Scleractinian Corals
title_short Evolution of Protein-Mediated Biomineralization in Scleractinian Corals
title_sort evolution of protein-mediated biomineralization in scleractinian corals
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902050/
https://www.ncbi.nlm.nih.gov/pubmed/33633782
http://dx.doi.org/10.3389/fgene.2021.618517
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