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COVID-19 in a temporal relation to the onset of multiple sclerosis

Neurological complications of COVID-19 have been described. We present the case of a 27-year-old woman who developed COVID-19 in April 2020. She continued to present anosmia and ageusia eight months later. Six months after contracting COVID-19, she developed dysesthesia, hypoesthesia and hyperreflex...

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Detalles Bibliográficos
Autores principales: Fragoso, Yara D., Pacheco, Filippe A.S., Silveira, Guilherme L., Oliveira, Rodrigo A., Carvalho, Vitor M., Martimbianco, Ana Luiza C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902206/
https://www.ncbi.nlm.nih.gov/pubmed/33662859
http://dx.doi.org/10.1016/j.msard.2021.102863
Descripción
Sumario:Neurological complications of COVID-19 have been described. We present the case of a 27-year-old woman who developed COVID-19 in April 2020. She continued to present anosmia and ageusia eight months later. Six months after contracting COVID-19, she developed dysesthesia, hypoesthesia and hyperreflexia. Her magnetic resonance imaging showed demyelinating lesions, of which two were enhanced by gadolinium. She was positive for oligoclonal bands in her spinal fluid. This patient developed multiple sclerosis with a temporal relationship to COVID-19. We believe that SARS-CoV-2 led to her autoimmune disease through a virus-induced neuroimmunopathological condition.