COVID-19 in a temporal relation to the onset of multiple sclerosis

Neurological complications of COVID-19 have been described. We present the case of a 27-year-old woman who developed COVID-19 in April 2020. She continued to present anosmia and ageusia eight months later. Six months after contracting COVID-19, she developed dysesthesia, hypoesthesia and hyperreflex...

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Autores principales: Fragoso, Yara D., Pacheco, Filippe A.S., Silveira, Guilherme L., Oliveira, Rodrigo A., Carvalho, Vitor M., Martimbianco, Ana Luiza C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902206/
https://www.ncbi.nlm.nih.gov/pubmed/33662859
http://dx.doi.org/10.1016/j.msard.2021.102863
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author Fragoso, Yara D.
Pacheco, Filippe A.S.
Silveira, Guilherme L.
Oliveira, Rodrigo A.
Carvalho, Vitor M.
Martimbianco, Ana Luiza C.
author_facet Fragoso, Yara D.
Pacheco, Filippe A.S.
Silveira, Guilherme L.
Oliveira, Rodrigo A.
Carvalho, Vitor M.
Martimbianco, Ana Luiza C.
author_sort Fragoso, Yara D.
collection PubMed
description Neurological complications of COVID-19 have been described. We present the case of a 27-year-old woman who developed COVID-19 in April 2020. She continued to present anosmia and ageusia eight months later. Six months after contracting COVID-19, she developed dysesthesia, hypoesthesia and hyperreflexia. Her magnetic resonance imaging showed demyelinating lesions, of which two were enhanced by gadolinium. She was positive for oligoclonal bands in her spinal fluid. This patient developed multiple sclerosis with a temporal relationship to COVID-19. We believe that SARS-CoV-2 led to her autoimmune disease through a virus-induced neuroimmunopathological condition.
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spelling pubmed-79022062021-02-24 COVID-19 in a temporal relation to the onset of multiple sclerosis Fragoso, Yara D. Pacheco, Filippe A.S. Silveira, Guilherme L. Oliveira, Rodrigo A. Carvalho, Vitor M. Martimbianco, Ana Luiza C. Mult Scler Relat Disord Correspondence Neurological complications of COVID-19 have been described. We present the case of a 27-year-old woman who developed COVID-19 in April 2020. She continued to present anosmia and ageusia eight months later. Six months after contracting COVID-19, she developed dysesthesia, hypoesthesia and hyperreflexia. Her magnetic resonance imaging showed demyelinating lesions, of which two were enhanced by gadolinium. She was positive for oligoclonal bands in her spinal fluid. This patient developed multiple sclerosis with a temporal relationship to COVID-19. We believe that SARS-CoV-2 led to her autoimmune disease through a virus-induced neuroimmunopathological condition. Elsevier B.V. 2021-05 2021-02-24 /pmc/articles/PMC7902206/ /pubmed/33662859 http://dx.doi.org/10.1016/j.msard.2021.102863 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Correspondence
Fragoso, Yara D.
Pacheco, Filippe A.S.
Silveira, Guilherme L.
Oliveira, Rodrigo A.
Carvalho, Vitor M.
Martimbianco, Ana Luiza C.
COVID-19 in a temporal relation to the onset of multiple sclerosis
title COVID-19 in a temporal relation to the onset of multiple sclerosis
title_full COVID-19 in a temporal relation to the onset of multiple sclerosis
title_fullStr COVID-19 in a temporal relation to the onset of multiple sclerosis
title_full_unstemmed COVID-19 in a temporal relation to the onset of multiple sclerosis
title_short COVID-19 in a temporal relation to the onset of multiple sclerosis
title_sort covid-19 in a temporal relation to the onset of multiple sclerosis
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902206/
https://www.ncbi.nlm.nih.gov/pubmed/33662859
http://dx.doi.org/10.1016/j.msard.2021.102863
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