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Single-cell mapper (scMappR): using scRNA-seq to infer the cell-type specificities of differentially expressed genes

RNA sequencing (RNA-seq) is widely used to identify differentially expressed genes (DEGs) and reveal biological mechanisms underlying complex biological processes. RNA-seq is often performed on heterogeneous samples and the resulting DEGs do not necessarily indicate the cell-types where the differen...

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Detalles Bibliográficos
Autores principales: Sokolowski, Dustin J, Faykoo-Martinez, Mariela, Erdman, Lauren, Hou, Huayun, Chan, Cadia, Zhu, Helen, Holmes, Melissa M, Goldenberg, Anna, Wilson, Michael D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902236/
https://www.ncbi.nlm.nih.gov/pubmed/33655208
http://dx.doi.org/10.1093/nargab/lqab011