Cargando…
Building research in diet and cognition (BRIDGE): Baseline characteristics of older obese African American adults in a randomized controlled trial to examine the effect of the Mediterranean diet with and without weight loss on cognitive functioning
In the United States, >5.4 million people age 65 and older are affected by cognitive impairment and dementia, including Alzheimer’s disease. African Americans are more likely than non-Hispanic whites to suffer from these disorders. Obesity is linked to accelerated age-related cognitive decline, a...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902520/ https://www.ncbi.nlm.nih.gov/pubmed/33665063 http://dx.doi.org/10.1016/j.pmedr.2020.101302 |
_version_ | 1783654541754892288 |
---|---|
author | Sanchez-Flack, Jennifer C. Tussing-Humphreys, Lisa Lamar, Melissa Fantuzzi, Giamilla Schiffer, Linda Blumstein, Lara McLeod, Andrew Dakers, Roxanne Strahan, Desmona Restrepo, Leo Hemphill, Nefertiti Oji Njideka Siegel, Leilah Antonic, Mirjana Fitzgibbon, Marian |
author_facet | Sanchez-Flack, Jennifer C. Tussing-Humphreys, Lisa Lamar, Melissa Fantuzzi, Giamilla Schiffer, Linda Blumstein, Lara McLeod, Andrew Dakers, Roxanne Strahan, Desmona Restrepo, Leo Hemphill, Nefertiti Oji Njideka Siegel, Leilah Antonic, Mirjana Fitzgibbon, Marian |
author_sort | Sanchez-Flack, Jennifer C. |
collection | PubMed |
description | In the United States, >5.4 million people age 65 and older are affected by cognitive impairment and dementia, including Alzheimer’s disease. African Americans are more likely than non-Hispanic whites to suffer from these disorders. Obesity is linked to accelerated age-related cognitive decline, and weight loss through caloric restriction is a potential strategy to prevent this cognitive impairment. Adherence to a healthful dietary pattern, such as the Mediterranean Diet (MedDiet), has also shown positive effects on reducing risk for dementia. African Americans are disproportionately affected by obesity and have less healthful diets than non-Hispanic whites. We present baseline characteristics from a three-arm randomized controlled trial that randomized 185 obese (BMI ≥ 30 kg/m(2) and ≤ 50 kg/m(2)) healthy older adults (55–85 years of age) to: 1) Typical Diet Control (TDC); 2) MedDiet alone (MedDiet-A) intervention; or 3) MedDiet caloric restricted intervention to promote weight loss (MedDiet-WL). The majority of the sample was African American (91.4%) and female (85.9%). The two active interventions (MedDiet-A and MedDiet-WL) met once weekly for 8 months, and the TDC received weekly general health newsletters. Baseline data were collected between January 2017 and July 2019 in Chicago, IL. In our sample, closer adherence to a MedDiet pattern was associated with higher attention and information processing (AIP) and higher executive functioning (EF). Consistent with the literature, we saw that older participants performed more poorly on the cognitive assessments than younger participants, and women outperformed men across verbally mediated tasks, especially ones related to learning and memory. |
format | Online Article Text |
id | pubmed-7902520 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
record_format | MEDLINE/PubMed |
spelling | pubmed-79025202021-03-03 Building research in diet and cognition (BRIDGE): Baseline characteristics of older obese African American adults in a randomized controlled trial to examine the effect of the Mediterranean diet with and without weight loss on cognitive functioning Sanchez-Flack, Jennifer C. Tussing-Humphreys, Lisa Lamar, Melissa Fantuzzi, Giamilla Schiffer, Linda Blumstein, Lara McLeod, Andrew Dakers, Roxanne Strahan, Desmona Restrepo, Leo Hemphill, Nefertiti Oji Njideka Siegel, Leilah Antonic, Mirjana Fitzgibbon, Marian Prev Med Rep Regular Article In the United States, >5.4 million people age 65 and older are affected by cognitive impairment and dementia, including Alzheimer’s disease. African Americans are more likely than non-Hispanic whites to suffer from these disorders. Obesity is linked to accelerated age-related cognitive decline, and weight loss through caloric restriction is a potential strategy to prevent this cognitive impairment. Adherence to a healthful dietary pattern, such as the Mediterranean Diet (MedDiet), has also shown positive effects on reducing risk for dementia. African Americans are disproportionately affected by obesity and have less healthful diets than non-Hispanic whites. We present baseline characteristics from a three-arm randomized controlled trial that randomized 185 obese (BMI ≥ 30 kg/m(2) and ≤ 50 kg/m(2)) healthy older adults (55–85 years of age) to: 1) Typical Diet Control (TDC); 2) MedDiet alone (MedDiet-A) intervention; or 3) MedDiet caloric restricted intervention to promote weight loss (MedDiet-WL). The majority of the sample was African American (91.4%) and female (85.9%). The two active interventions (MedDiet-A and MedDiet-WL) met once weekly for 8 months, and the TDC received weekly general health newsletters. Baseline data were collected between January 2017 and July 2019 in Chicago, IL. In our sample, closer adherence to a MedDiet pattern was associated with higher attention and information processing (AIP) and higher executive functioning (EF). Consistent with the literature, we saw that older participants performed more poorly on the cognitive assessments than younger participants, and women outperformed men across verbally mediated tasks, especially ones related to learning and memory. 2020-12-31 /pmc/articles/PMC7902520/ /pubmed/33665063 http://dx.doi.org/10.1016/j.pmedr.2020.101302 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Regular Article Sanchez-Flack, Jennifer C. Tussing-Humphreys, Lisa Lamar, Melissa Fantuzzi, Giamilla Schiffer, Linda Blumstein, Lara McLeod, Andrew Dakers, Roxanne Strahan, Desmona Restrepo, Leo Hemphill, Nefertiti Oji Njideka Siegel, Leilah Antonic, Mirjana Fitzgibbon, Marian Building research in diet and cognition (BRIDGE): Baseline characteristics of older obese African American adults in a randomized controlled trial to examine the effect of the Mediterranean diet with and without weight loss on cognitive functioning |
title | Building research in diet and cognition (BRIDGE): Baseline characteristics of older obese African American adults in a randomized controlled trial to examine the effect of the Mediterranean diet with and without weight loss on cognitive functioning |
title_full | Building research in diet and cognition (BRIDGE): Baseline characteristics of older obese African American adults in a randomized controlled trial to examine the effect of the Mediterranean diet with and without weight loss on cognitive functioning |
title_fullStr | Building research in diet and cognition (BRIDGE): Baseline characteristics of older obese African American adults in a randomized controlled trial to examine the effect of the Mediterranean diet with and without weight loss on cognitive functioning |
title_full_unstemmed | Building research in diet and cognition (BRIDGE): Baseline characteristics of older obese African American adults in a randomized controlled trial to examine the effect of the Mediterranean diet with and without weight loss on cognitive functioning |
title_short | Building research in diet and cognition (BRIDGE): Baseline characteristics of older obese African American adults in a randomized controlled trial to examine the effect of the Mediterranean diet with and without weight loss on cognitive functioning |
title_sort | building research in diet and cognition (bridge): baseline characteristics of older obese african american adults in a randomized controlled trial to examine the effect of the mediterranean diet with and without weight loss on cognitive functioning |
topic | Regular Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902520/ https://www.ncbi.nlm.nih.gov/pubmed/33665063 http://dx.doi.org/10.1016/j.pmedr.2020.101302 |
work_keys_str_mv | AT sanchezflackjenniferc buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT tussinghumphreyslisa buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT lamarmelissa buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT fantuzzigiamilla buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT schifferlinda buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT blumsteinlara buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT mcleodandrew buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT dakersroxanne buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT strahandesmona buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT restrepoleo buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT hemphillnefertitiojinjideka buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT siegelleilah buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT antonicmirjana buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning AT fitzgibbonmarian buildingresearchindietandcognitionbridgebaselinecharacteristicsofolderobeseafricanamericanadultsinarandomizedcontrolledtrialtoexaminetheeffectofthemediterraneandietwithandwithoutweightlossoncognitivefunctioning |