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Maternal pre-pregnancy body mass index and foetal acidosis in vaginal and caesarean deliveries: The Japan Environment and Children’s Study

A high maternal body mass index (BMI) is associated with increased risks of asphyxia-related neonatal morbidity. We evaluated the association between maternal pre-pregnancy BMI and foetal acidosis while accounting for the mode of delivery. Participants from the Japan Environment and Children’s Study...

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Autores principales: Murata, Tsuyoshi, Kyozuka, Hyo, Yamaguchi, Akiko, Fukuda, Toma, Yasuda, Shun, Sato, Akiko, Ogata, Yuka, Shinoki, Kosei, Hosoya, Mitsuaki, Yasumura, Seiji, Hashimoto, Koichi, Nishigori, Hidekazu, Fujimori, Keiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902605/
https://www.ncbi.nlm.nih.gov/pubmed/33623113
http://dx.doi.org/10.1038/s41598-020-79178-1
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author Murata, Tsuyoshi
Kyozuka, Hyo
Yamaguchi, Akiko
Fukuda, Toma
Yasuda, Shun
Sato, Akiko
Ogata, Yuka
Shinoki, Kosei
Hosoya, Mitsuaki
Yasumura, Seiji
Hashimoto, Koichi
Nishigori, Hidekazu
Fujimori, Keiya
author_facet Murata, Tsuyoshi
Kyozuka, Hyo
Yamaguchi, Akiko
Fukuda, Toma
Yasuda, Shun
Sato, Akiko
Ogata, Yuka
Shinoki, Kosei
Hosoya, Mitsuaki
Yasumura, Seiji
Hashimoto, Koichi
Nishigori, Hidekazu
Fujimori, Keiya
author_sort Murata, Tsuyoshi
collection PubMed
description A high maternal body mass index (BMI) is associated with increased risks of asphyxia-related neonatal morbidity. We evaluated the association between maternal pre-pregnancy BMI and foetal acidosis while accounting for the mode of delivery. Participants from the Japan Environment and Children’s Study with singleton pregnancies after 22 weeks of gestation who gave birth during 2011–2014 were included. The participants (n = 71,799) were categorised into five groups according to the pre-pregnancy BMI: G1 (BMI < 18.5 kg/m(2)), G2 (18.5 to < 20.0 kg/m(2)), G3 (20.0 to < 23.0 kg/m(2)), G4 (23.0 to < 25.0 kg/m(2)), and G5 (≥ 25.0 kg/m(2)). Foetal acidosis was defined as umbilical artery pH (UmA-pH) < 7.20 or < 7.10. Multiple logistic regression analyses were used to evaluate the effect of pre-pregnancy BMI on foetal acidosis risk, accounting for the mode of delivery. In Japanese women, pre-pregnancy BMI ≥ 25.0 kg/m(2) significantly increased the likelihood of foetal acidosis in newborns delivered vaginally. We found no association between pre-pregnancy BMI and foetal acidosis in newborns delivered via caesarean section. Counselling for body weight control before pregnancy and adequate management and selection of the mode of delivery in pregnant women with a high BMI who are in labour may be essential to avoid foetal acidosis.
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spelling pubmed-79026052021-02-24 Maternal pre-pregnancy body mass index and foetal acidosis in vaginal and caesarean deliveries: The Japan Environment and Children’s Study Murata, Tsuyoshi Kyozuka, Hyo Yamaguchi, Akiko Fukuda, Toma Yasuda, Shun Sato, Akiko Ogata, Yuka Shinoki, Kosei Hosoya, Mitsuaki Yasumura, Seiji Hashimoto, Koichi Nishigori, Hidekazu Fujimori, Keiya Sci Rep Article A high maternal body mass index (BMI) is associated with increased risks of asphyxia-related neonatal morbidity. We evaluated the association between maternal pre-pregnancy BMI and foetal acidosis while accounting for the mode of delivery. Participants from the Japan Environment and Children’s Study with singleton pregnancies after 22 weeks of gestation who gave birth during 2011–2014 were included. The participants (n = 71,799) were categorised into five groups according to the pre-pregnancy BMI: G1 (BMI < 18.5 kg/m(2)), G2 (18.5 to < 20.0 kg/m(2)), G3 (20.0 to < 23.0 kg/m(2)), G4 (23.0 to < 25.0 kg/m(2)), and G5 (≥ 25.0 kg/m(2)). Foetal acidosis was defined as umbilical artery pH (UmA-pH) < 7.20 or < 7.10. Multiple logistic regression analyses were used to evaluate the effect of pre-pregnancy BMI on foetal acidosis risk, accounting for the mode of delivery. In Japanese women, pre-pregnancy BMI ≥ 25.0 kg/m(2) significantly increased the likelihood of foetal acidosis in newborns delivered vaginally. We found no association between pre-pregnancy BMI and foetal acidosis in newborns delivered via caesarean section. Counselling for body weight control before pregnancy and adequate management and selection of the mode of delivery in pregnant women with a high BMI who are in labour may be essential to avoid foetal acidosis. Nature Publishing Group UK 2021-02-23 /pmc/articles/PMC7902605/ /pubmed/33623113 http://dx.doi.org/10.1038/s41598-020-79178-1 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Murata, Tsuyoshi
Kyozuka, Hyo
Yamaguchi, Akiko
Fukuda, Toma
Yasuda, Shun
Sato, Akiko
Ogata, Yuka
Shinoki, Kosei
Hosoya, Mitsuaki
Yasumura, Seiji
Hashimoto, Koichi
Nishigori, Hidekazu
Fujimori, Keiya
Maternal pre-pregnancy body mass index and foetal acidosis in vaginal and caesarean deliveries: The Japan Environment and Children’s Study
title Maternal pre-pregnancy body mass index and foetal acidosis in vaginal and caesarean deliveries: The Japan Environment and Children’s Study
title_full Maternal pre-pregnancy body mass index and foetal acidosis in vaginal and caesarean deliveries: The Japan Environment and Children’s Study
title_fullStr Maternal pre-pregnancy body mass index and foetal acidosis in vaginal and caesarean deliveries: The Japan Environment and Children’s Study
title_full_unstemmed Maternal pre-pregnancy body mass index and foetal acidosis in vaginal and caesarean deliveries: The Japan Environment and Children’s Study
title_short Maternal pre-pregnancy body mass index and foetal acidosis in vaginal and caesarean deliveries: The Japan Environment and Children’s Study
title_sort maternal pre-pregnancy body mass index and foetal acidosis in vaginal and caesarean deliveries: the japan environment and children’s study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902605/
https://www.ncbi.nlm.nih.gov/pubmed/33623113
http://dx.doi.org/10.1038/s41598-020-79178-1
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