Safety and efficacy of combination of suberoylamilide hydroxyamic acid and mitomycin C in reducing pro-fibrotic changes in human corneal epithelial cells

Corneal haze post refractive surgery is prevented by mitomycin c (MMC) treatment though it can lead to corneal endothelial damage, persistent epithelial defects and necrosis of cells. Suberanilohydroxamic acid (SAHA) however has been proposed to prevent corneal haze without any adverse effects. For...

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Detalles Bibliográficos
Autores principales: Shetty, Rohit, Kumar, Nimisha Rajiv, Subramani, Murali, Krishna, Lekshmi, Murugeswari, Ponnalagu, Matalia, Himanshu, Khamar, Pooja, Dadachanji, Zelda V., Mohan, Rajiv R., Ghosh, Arkasubhra, Das, Debashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902619/
https://www.ncbi.nlm.nih.gov/pubmed/33623133
http://dx.doi.org/10.1038/s41598-021-83881-y

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