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Automatic segmentation of inner ear on CT-scan using auto-context convolutional neural network

Temporal bone CT-scan is a prerequisite in most surgical procedures concerning the ear such as cochlear implants. The 3D vision of inner ear structures is crucial for diagnostic and surgical preplanning purposes. Since clinical CT-scans are acquired at relatively low resolutions, improved performanc...

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Autores principales: Hussain, Raabid, Lalande, Alain, Girum, Kibrom Berihu, Guigou, Caroline, Bozorg Grayeli, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902630/
https://www.ncbi.nlm.nih.gov/pubmed/33623074
http://dx.doi.org/10.1038/s41598-021-83955-x
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author Hussain, Raabid
Lalande, Alain
Girum, Kibrom Berihu
Guigou, Caroline
Bozorg Grayeli, Alexis
author_facet Hussain, Raabid
Lalande, Alain
Girum, Kibrom Berihu
Guigou, Caroline
Bozorg Grayeli, Alexis
author_sort Hussain, Raabid
collection PubMed
description Temporal bone CT-scan is a prerequisite in most surgical procedures concerning the ear such as cochlear implants. The 3D vision of inner ear structures is crucial for diagnostic and surgical preplanning purposes. Since clinical CT-scans are acquired at relatively low resolutions, improved performance can be achieved by registering patient-specific CT images to a high-resolution inner ear model built from accurate 3D segmentations based on micro-CT of human temporal bone specimens. This paper presents a framework based on convolutional neural network for human inner ear segmentation from micro-CT images which can be used to build such a model from an extensive database. The proposed approach employs an auto-context based cascaded 2D U-net architecture with 3D connected component refinement to segment the cochlear scalae, semicircular canals, and the vestibule. The system was formulated on a data set composed of 17 micro-CT from public Hear-EU dataset. A Dice coefficient of 0.90 and Hausdorff distance of 0.74 mm were obtained. The system yielded precise and fast automatic inner-ear segmentations.
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spelling pubmed-79026302021-02-24 Automatic segmentation of inner ear on CT-scan using auto-context convolutional neural network Hussain, Raabid Lalande, Alain Girum, Kibrom Berihu Guigou, Caroline Bozorg Grayeli, Alexis Sci Rep Article Temporal bone CT-scan is a prerequisite in most surgical procedures concerning the ear such as cochlear implants. The 3D vision of inner ear structures is crucial for diagnostic and surgical preplanning purposes. Since clinical CT-scans are acquired at relatively low resolutions, improved performance can be achieved by registering patient-specific CT images to a high-resolution inner ear model built from accurate 3D segmentations based on micro-CT of human temporal bone specimens. This paper presents a framework based on convolutional neural network for human inner ear segmentation from micro-CT images which can be used to build such a model from an extensive database. The proposed approach employs an auto-context based cascaded 2D U-net architecture with 3D connected component refinement to segment the cochlear scalae, semicircular canals, and the vestibule. The system was formulated on a data set composed of 17 micro-CT from public Hear-EU dataset. A Dice coefficient of 0.90 and Hausdorff distance of 0.74 mm were obtained. The system yielded precise and fast automatic inner-ear segmentations. Nature Publishing Group UK 2021-02-23 /pmc/articles/PMC7902630/ /pubmed/33623074 http://dx.doi.org/10.1038/s41598-021-83955-x Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Hussain, Raabid
Lalande, Alain
Girum, Kibrom Berihu
Guigou, Caroline
Bozorg Grayeli, Alexis
Automatic segmentation of inner ear on CT-scan using auto-context convolutional neural network
title Automatic segmentation of inner ear on CT-scan using auto-context convolutional neural network
title_full Automatic segmentation of inner ear on CT-scan using auto-context convolutional neural network
title_fullStr Automatic segmentation of inner ear on CT-scan using auto-context convolutional neural network
title_full_unstemmed Automatic segmentation of inner ear on CT-scan using auto-context convolutional neural network
title_short Automatic segmentation of inner ear on CT-scan using auto-context convolutional neural network
title_sort automatic segmentation of inner ear on ct-scan using auto-context convolutional neural network
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902630/
https://www.ncbi.nlm.nih.gov/pubmed/33623074
http://dx.doi.org/10.1038/s41598-021-83955-x
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