Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins

Flaviviruses such as Dengue (DENV) or Zika virus (ZIKV) assemble into an immature form within the endoplasmatic reticulum (ER), and are then processed by furin protease in the trans-Golgi. To better grasp maturation, we carry out cryo-EM reconstructions of immature Spondweni virus (SPOV), a human fl...

Descripción completa

Detalles Bibliográficos
Autores principales: Renner, Max, Dejnirattisai, Wanwisa, Carrique, Loïc, Martin, Itziar Serna, Karia, Dimple, Ilca, Serban L., Ho, Shu F., Kotecha, Abhay, Keown, Jeremy R., Mongkolsapaya, Juthathip, Screaton, Gavin R., Grimes, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902656/
https://www.ncbi.nlm.nih.gov/pubmed/33623019
http://dx.doi.org/10.1038/s41467-021-21505-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902656/
https://www.ncbi.nlm.nih.gov/pubmed/33623019
http://dx.doi.org/10.1038/s41467-021-21505-9

Ejemplares similares