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Screening of metabolic modulators identifies new strategies to target metabolic reprogramming in melanoma

The prognosis of metastatic melanoma remains poor due to de novo or acquired resistance to immune and targeted therapies. Previous studies have shown that melanoma cells have perturbed metabolism and that cellular metabolic pathways represent potential therapeutic targets. To support the discovery o...

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Detalles Bibliográficos
Autores principales: Abildgaard, Cecilie, Rizza, Salvatore, Christiansen, Helle, Schmidt, Steffen, Dahl, Christina, Abdul-Al, Ahmad, Christensen, Annette, Filomeni, Giuseppe, Guldberg, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902673/
https://www.ncbi.nlm.nih.gov/pubmed/33623106
http://dx.doi.org/10.1038/s41598-021-83796-8