Case Report: Insulin-Dependent Diabetes Mellitus and Diabetic Keto-Acidosis in a Child With COVID-19

During the COVID pandemic, a surge in pediatric Type 1 Diabetes Mellitus (T1DM) cases appears to be occurring, potentially due to the presence of autoantibody-induced immune dysregulation triggered by COVID-19. We describe one such case in a previously healthy 7-year-old with asymptomatic COVID-19 p...

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Autores principales: Nielsen-Saines, Karin, Li, Erica, Olivera, Adriana Martinez, Martin-Blais, Rachel, Bulut, Yonca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902688/
https://www.ncbi.nlm.nih.gov/pubmed/33643977
http://dx.doi.org/10.3389/fped.2021.628810
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author Nielsen-Saines, Karin
Li, Erica
Olivera, Adriana Martinez
Martin-Blais, Rachel
Bulut, Yonca
author_facet Nielsen-Saines, Karin
Li, Erica
Olivera, Adriana Martinez
Martin-Blais, Rachel
Bulut, Yonca
author_sort Nielsen-Saines, Karin
collection PubMed
description During the COVID pandemic, a surge in pediatric Type 1 Diabetes Mellitus (T1DM) cases appears to be occurring, potentially due to the presence of autoantibody-induced immune dysregulation triggered by COVID-19. We describe one such case in a previously healthy 7-year-old with asymptomatic COVID-19 presenting with a high nasopharyngeal SARS CoV-2 virus load, detectable COVID-19 IgG antibodies, diabetic keto-acidosis and islet cell autoantibodies. COVID-19 is not a trivial disease in children and adolescents and can lead to lifelong sequelae such as T1DM. Raising awareness about a possible association between COVID-19 and T1DM in children is critical.
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spelling pubmed-79026882021-02-25 Case Report: Insulin-Dependent Diabetes Mellitus and Diabetic Keto-Acidosis in a Child With COVID-19 Nielsen-Saines, Karin Li, Erica Olivera, Adriana Martinez Martin-Blais, Rachel Bulut, Yonca Front Pediatr Pediatrics During the COVID pandemic, a surge in pediatric Type 1 Diabetes Mellitus (T1DM) cases appears to be occurring, potentially due to the presence of autoantibody-induced immune dysregulation triggered by COVID-19. We describe one such case in a previously healthy 7-year-old with asymptomatic COVID-19 presenting with a high nasopharyngeal SARS CoV-2 virus load, detectable COVID-19 IgG antibodies, diabetic keto-acidosis and islet cell autoantibodies. COVID-19 is not a trivial disease in children and adolescents and can lead to lifelong sequelae such as T1DM. Raising awareness about a possible association between COVID-19 and T1DM in children is critical. Frontiers Media S.A. 2021-02-10 /pmc/articles/PMC7902688/ /pubmed/33643977 http://dx.doi.org/10.3389/fped.2021.628810 Text en Copyright © 2021 Nielsen-Saines, Li, Olivera, Martin-Blais and Bulut. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Nielsen-Saines, Karin
Li, Erica
Olivera, Adriana Martinez
Martin-Blais, Rachel
Bulut, Yonca
Case Report: Insulin-Dependent Diabetes Mellitus and Diabetic Keto-Acidosis in a Child With COVID-19
title Case Report: Insulin-Dependent Diabetes Mellitus and Diabetic Keto-Acidosis in a Child With COVID-19
title_full Case Report: Insulin-Dependent Diabetes Mellitus and Diabetic Keto-Acidosis in a Child With COVID-19
title_fullStr Case Report: Insulin-Dependent Diabetes Mellitus and Diabetic Keto-Acidosis in a Child With COVID-19
title_full_unstemmed Case Report: Insulin-Dependent Diabetes Mellitus and Diabetic Keto-Acidosis in a Child With COVID-19
title_short Case Report: Insulin-Dependent Diabetes Mellitus and Diabetic Keto-Acidosis in a Child With COVID-19
title_sort case report: insulin-dependent diabetes mellitus and diabetic keto-acidosis in a child with covid-19
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902688/
https://www.ncbi.nlm.nih.gov/pubmed/33643977
http://dx.doi.org/10.3389/fped.2021.628810
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