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Befriending the Hostile Tumor Microenvironment in CAR T-Cell Therapy

T-cells genetically engineered to express a chimeric antigen receptor (CAR) have shown remarkable results in patients with B-cell malignancies, including B-cell acute lymphoblastic leukemia, diffuse large B-cell lymphoma, and mantle cell lymphoma, with some promising efficacy in patients with multip...

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Detalles Bibliográficos
Autores principales:	Lindo, Lorenzo, Wilkinson, Lauren Hanna, Hay, Kevin Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902760/ https://www.ncbi.nlm.nih.gov/pubmed/33643299 http://dx.doi.org/10.3389/fimmu.2020.618387

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