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Interleukin-1β Modulates Synaptic Transmission and Synaptic Plasticity During the Acute Phase of Sepsis in the Senescence-Accelerated Mouse Hippocampus

BACKGROUND: Aging and pre-existing cognitive impairment are considered to be independent risk factors for sepsis-associated encephalopathy. This study aimed to investigate the manner in which aging and pre-existing cognitive dysfunction modified neuroinflammation, synaptic plasticity, and basal syna...

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Detalles Bibliográficos
Autores principales:	Hoshino, Koji, Uchinami, Yuka, Uchida, Yosuke, Saito, Hitoshi, Morimoto, Yuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902794/ https://www.ncbi.nlm.nih.gov/pubmed/33643027 http://dx.doi.org/10.3389/fnagi.2021.637703

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