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The lytic polysaccharide monooxygenase CbpD promotes Pseudomonas aeruginosa virulence in systemic infection

The recently discovered lytic polysaccharide monooxygenases (LPMOs), which cleave polysaccharides by oxidation, have been associated with bacterial virulence, but supporting functional data is scarce. Here we show that CbpD, the LPMO of Pseudomonas aeruginosa, is a chitin-oxidizing virulence factor...

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Detalles Bibliográficos
Autores principales:	Askarian, Fatemeh, Uchiyama, Satoshi, Masson, Helen, Sørensen, Henrik Vinther, Golten, Ole, Bunæs, Anne Cathrine, Mekasha, Sophanit, Røhr, Åsmund Kjendseth, Kommedal, Eirik, Ludviksen, Judith Anita, Arntzen, Magnus Ø., Schmidt, Benjamin, Zurich, Raymond H., van Sorge, Nina M., Eijsink, Vincent G. H., Krengel, Ute, Mollnes, Tom Eirik, Lewis, Nathan E., Nizet, Victor, Vaaje-Kolstad, Gustav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902821/ https://www.ncbi.nlm.nih.gov/pubmed/33623002 http://dx.doi.org/10.1038/s41467-021-21473-0

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