Facilitative lysosomal transport of bile acids alleviates ER stress in mouse hematopoietic precursors

Mutations in human equilibrative nucleoside transporter 3 (ENT3) encoded by SLC29A3 results in anemia and erythroid hypoplasia, suggesting that ENT3 may regulate erythropoiesis. Here, we demonstrate that lysosomal ENT3 transport of taurine-conjugated bile acids (TBA) facilitates TBA chemical chapero...

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Detalles Bibliográficos
Autores principales: Persaud, Avinash K., Nair, Sreenath, Rahman, Md Fazlur, Raj, Radhika, Weadick, Brenna, Nayak, Debasis, McElroy, Craig, Shanmugam, Muruganandan, Knoblaugh, Sue, Cheng, Xiaolin, Govindarajan, Rajgopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902824/
https://www.ncbi.nlm.nih.gov/pubmed/33623001
http://dx.doi.org/10.1038/s41467-021-21451-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902824/
https://www.ncbi.nlm.nih.gov/pubmed/33623001
http://dx.doi.org/10.1038/s41467-021-21451-6

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