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Endogenous complement human serum bactericidal assay (enc-hSBA) for vaccine effectiveness assessments against meningococcal serogroup B

Immunogenicity of vaccines against meningococcal serogroup B (MenB) has been assessed pre-licensure with a human serum bactericidal activity assay (hSBA), tested against small numbers of strains. We report the qualification/validation of an alternative qualitative hSBA which uses endogenous compleme...

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Detalles Bibliográficos
Autores principales:	Kleinschmidt, Annett, Vadivelu, Kumaran, Serino, Laura, Neidig, Nina, de Wergifosse, Bertrand
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902841/ https://www.ncbi.nlm.nih.gov/pubmed/33623041 http://dx.doi.org/10.1038/s41541-021-00286-8

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