Cargando…

Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients

Objectives: To evaluate the impact of SNCA polymorphisms originally identified as risk factors for Parkinson's disease (PD) on the clinical presentation and progression of the disease in a large cohort of population-based patients with incident PD. Methods: Four hundred thirty-three patients an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Szwedo, Aleksandra A., Pedersen, Camilla Christina, Ushakova, Anastasia, Forsgren, Lars, Tysnes, Ole-Bjørn, Counsell, Carl E., Alves, Guido, Lange, Johannes, Macleod, Angus D., Maple-Grødem, Jodi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902914/ https://www.ncbi.nlm.nih.gov/pubmed/33643180 http://dx.doi.org/10.3389/fneur.2020.620585

Ejemplares similares

Association of GBA Genotype With Motor and Functional Decline in Patients With Newly Diagnosed Parkinson Disease
por: Maple-Grødem, Jodi, et al.
Publicado: (2021)

Inflammatory Biomarkers in Newly Diagnosed Patients With Parkinson Disease and Related Neurodegenerative Disorders
por: Pedersen, Camilla Christina, et al.
Publicado: (2023)

A systematic review of associations between common SNCA variants and clinical heterogeneity in Parkinson’s disease
por: Pedersen, Camilla Christina, et al.
Publicado: (2021)

Seed Amplification Assay as a Diagnostic Tool in Newly-Diagnosed Parkinson’s Disease
por: Oftedal, Linn, et al.
Publicado: (2023)

Dopaminergic and Opioid Pathways Associated with Impulse Control Disorders in Parkinson’s Disease
por: Erga, Aleksander H., et al.
Publicado: (2018)

Association of CSF Glucocerebrosidase Activity With the Risk of Incident Dementia in Patients With Parkinson Disease
por: Oftedal, Linn, et al.
Publicado: (2023)

GBA and APOE Impact Cognitive Decline in Parkinson’s Disease: A 10-Year Population-Based Study
por: Szwedo, Aleksandra A., et al.
Publicado: (2022)

Development and validation of prognostic survival models in newly diagnosed Parkinson's disease
por: Macleod, Angus D., et al.
Publicado: (2017)

Parkinson’s disease clinical milestones and mortality
por: Gonzalez, Maria Camila, et al.
Publicado: (2022)

The incidence, baseline predictors, and outcomes of dementia in an incident cohort of Parkinson’s disease and controls
por: Counsell, Carl, et al.
Publicado: (2022)

Early GCase activity is a predictor of long-term cognitive decline in Parkinson’s disease
por: Oftedal, Linn, et al.
Publicado: (2023)

Lack of Association Between GBA Mutations and Motor Complications in European and American Parkinson’s Disease Cohorts
por: Maple-Grødem, Jodi, et al.
Publicado: (2021)

Association of a BACE1 Gene Polymorphism with Parkinson's Disease in a Norwegian Population
por: Lange, Johannes, et al.
Publicado: (2015)

First delirium episode in Parkinson’s disease and parkinsonism: incidence, predictors, and outcomes
por: Green, Samantha, et al.
Publicado: (2021)

Rare genetic variation in mitochondrial pathways influences the risk for Parkinson's disease
por: Gaare, Johannes J., et al.
Publicado: (2018)

Excessive Daytime Sleepiness and REM Sleep Behavior Disorders in Parkinson's Disease: A Narrative Review on Early Intervention With Implications to Neuroprotection
por: Gjerstad, Michaela D., et al.
Publicado: (2018)

Genetic risk scores and hallucinations in patients with Parkinson disease
por: Kusters, Cynthia D.J., et al.
Publicado: (2020)

Validation and assessment of preanalytical factors of a fluorometric in vitro assay for glucocerebrosidase activity in human cerebrospinal fluid
por: Oftedal, Linn, et al.
Publicado: (2020)

Predictors of functional dependency in Parkinson's disease
por: Macleod, Angus D., et al.
Publicado: (2016)

Cognitive Profile in Parkinson’s Disease Dementia Patients with Low versus Normal Cerebrospinal Fluid Amyloid Beta
por: Tufekcioglu, Zeynep, et al.
Publicado: (2023)

Evolution of impulsive–compulsive behaviors and cognition in Parkinson’s disease
por: Erga, Aleksander H., et al.
Publicado: (2019)

SNCA-AS1 in aging and Parkinson’s disease
por: Carelli, Stephana, et al.
Publicado: (2022)

The SNCA-Rep1 Polymorphic Locus: Association with the Risk of Parkinson’s Disease and SNCA Gene Methylation
por: Iakovenko, E. V., et al.
Publicado: (2020)

Co-morbidity burden in Parkinson’s disease: Comparison with controls and its influence on prognosis
por: Macleod, Angus D., et al.
Publicado: (2016)

Variants in the SNCA Locus Are Associated With the Progression of Parkinson's Disease
por: Luo, Ningdi, et al.
Publicado: (2019)

Reliability of Three Disability Scales for Detection of Independence Loss in Parkinson's Disease
por: Bjornestad, Anders, et al.
Publicado: (2016)

Evaluation of the Role of SNCA Variants in Survival without Neurological Disease
por: Heckman, Michael G., et al.
Publicado: (2012)

Mutations in PRKN and SNCA Genes Important for the Progress of Parkinson’s Disease
por: Oczkowska, Anna, et al.
Publicado: (2013)

Festination Correlates with SNCA Polymorphism in Chinese Patients with Parkinson's Disease
por: Zheng, Jinhua, et al.
Publicado: (2017)

Genetic Analysis and Literature Review of SNCA Variants in Parkinson's Disease
por: Guo, Yi, et al.
Publicado: (2021)

SNCA 3′ UTR Genetic Variants in Patients with Parkinson’s Disease
por: Blažeković, Antonela, et al.
Publicado: (2021)

SNCA Gene Methylation in Parkinson’s Disease and Multiple System Atrophy
por: Fedotova, Ekaterina Yu., et al.
Publicado: (2023)

Early constipation predicts faster dementia onset in Parkinson’s disease
por: Camacho, M., et al.
Publicado: (2021)

Development of a constitutive and an auto-inducible high-yield expression system for recombinant protein production in the microalga Nannochloropsis oceanica
por: de Grahl, Imke, et al.
Publicado: (2020)

Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson’s disease
por: Dick, Fiona, et al.
Publicado: (2023)

The Parkinson Disease gene SNCA: Evolutionary and structural insights with pathological implication
por: Siddiqui, Irum Javaid, et al.
Publicado: (2016)

Impulsive and Compulsive Behaviors in Parkinson’s Disease: The Norwegian ParkWest Study
por: Erga, Aleksander H., et al.
Publicado: (2017)

SNCA and MAPT genes: Independent and joint effects in Parkinson disease in the Italian population
por: Trotta, Luca, et al.
Publicado: (2012)

SNCA Gene, but Not MAPT, Influences Onset Age of Parkinson's Disease in Chinese and Australians
por: Huang, Yue, et al.
Publicado: (2015)

A Comprehensive Analysis of the Association Between SNCA Polymorphisms and the Risk of Parkinson's Disease
por: Zhang, Yuan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vu62t2m1giuccn75eiljdcfq5u