Autophagy as a Vital Therapy Target for Renal Cell Carcinoma

Autophagy is a process that degrades and recycles superfluous organelles or damaged cellular contents. It has been found to have dual functions in renal cell carcinoma (RCC). Many autophagy-related proteins are regarded as prognostic markers of RCC. Researchers have attempted to explore synthetic an...

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Detalles Bibliográficos
Autores principales: He, Ying-hua, Tian, Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902926/
https://www.ncbi.nlm.nih.gov/pubmed/33643028
http://dx.doi.org/10.3389/fphar.2020.518225
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author He, Ying-hua
Tian, Guo
author_facet He, Ying-hua
Tian, Guo
author_sort He, Ying-hua
collection PubMed
description Autophagy is a process that degrades and recycles superfluous organelles or damaged cellular contents. It has been found to have dual functions in renal cell carcinoma (RCC). Many autophagy-related proteins are regarded as prognostic markers of RCC. Researchers have attempted to explore synthetic and phytochemical drugs for RCC therapy that target autophagy. In this review, we highlight the importance of autophagy in RCC and potential treatments related to autophagy.
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spelling pubmed-79029262021-02-25 Autophagy as a Vital Therapy Target for Renal Cell Carcinoma He, Ying-hua Tian, Guo Front Pharmacol Pharmacology Autophagy is a process that degrades and recycles superfluous organelles or damaged cellular contents. It has been found to have dual functions in renal cell carcinoma (RCC). Many autophagy-related proteins are regarded as prognostic markers of RCC. Researchers have attempted to explore synthetic and phytochemical drugs for RCC therapy that target autophagy. In this review, we highlight the importance of autophagy in RCC and potential treatments related to autophagy. Frontiers Media S.A. 2021-02-10 /pmc/articles/PMC7902926/ /pubmed/33643028 http://dx.doi.org/10.3389/fphar.2020.518225 Text en Copyright © 2021 He and Tian. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (http://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
He, Ying-hua
Tian, Guo
Autophagy as a Vital Therapy Target for Renal Cell Carcinoma
title Autophagy as a Vital Therapy Target for Renal Cell Carcinoma
title_full Autophagy as a Vital Therapy Target for Renal Cell Carcinoma
title_fullStr Autophagy as a Vital Therapy Target for Renal Cell Carcinoma
title_full_unstemmed Autophagy as a Vital Therapy Target for Renal Cell Carcinoma
title_short Autophagy as a Vital Therapy Target for Renal Cell Carcinoma
title_sort autophagy as a vital therapy target for renal cell carcinoma
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902926/
https://www.ncbi.nlm.nih.gov/pubmed/33643028
http://dx.doi.org/10.3389/fphar.2020.518225
work_keys_str_mv AT heyinghua autophagyasavitaltherapytargetforrenalcellcarcinoma
AT tianguo autophagyasavitaltherapytargetforrenalcellcarcinoma

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