Cargando…

The Dynamics of Metabolic Characterization in iPSC-Derived Kidney Organoid Differentiation via a Comparative Omics Approach

The use of differentiating human induced pluripotent stem cells (hiPSCs) in mini-tissue organoids provides an invaluable resource for regenerative medicine applications, particularly in the field of disease modeling. However, most studies using a kidney organoid model, focused solely on the transcri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Qizheng, Xiong, Yucui, Zhang, Sheng, Sui, Yufei, Yu, Cunlai, Liu, Peng, Li, Heying, Guo, Wenjing, Gao, Yubo, Przepiorski, Aneta, Davidson, Alan J., Guo, Meijin, Zhang, Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902935/ https://www.ncbi.nlm.nih.gov/pubmed/33643392 http://dx.doi.org/10.3389/fgene.2021.632810

Ejemplares similares

Merits and challenges of iPSC-derived organoids for clinical applications
por: Xu, Ziran, et al.
Publicado: (2023)

Application of an iPSC‐Derived Organoid Model for Localized Scleroderma Therapy
por: Ma, Jie, et al.
Publicado: (2022)

Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids
por: Sun, Guoqiang, et al.
Publicado: (2020)

iPSC-Derived Organoids as Therapeutic Models in Regenerative Medicine and Oncology
por: Turhan, Ali G., et al.
Publicado: (2021)

iPSC-derived mesenchymal cells that support alveolar organoid development
por: Tamai, Koji, et al.
Publicado: (2022)

Generation and validation of APOE knockout human iPSC-derived cerebral organoids
por: Martens, Yuka A., et al.
Publicado: (2021)

Human iPSC colon organoid function is improved by exposure to fecal fermentates
por: Pearce, Sarah C., et al.
Publicado: (2022)

The Histone Demethylase JMJD2A Modulates the Induction of Hypertrophy Markers in iPSC-Derived Cardiomyocytes
por: Rosales, Wendy, et al.
Publicado: (2018)

Protocol for Large-Scale Production of Kidney Organoids from Human Pluripotent Stem Cells
por: Sander, Veronika, et al.
Publicado: (2020)

Advancing Drug Discovery for Neurological Disorders Using iPSC-Derived Neural Organoids
por: Costamagna, Gianluca, et al.
Publicado: (2021)

“iPSC-derived liver organoids and inherited bleeding disorders: Potential and future perspectives”
por: Roman, Giacomo, et al.
Publicado: (2023)

iPSC-derived three-dimensional brain organoid models and neurotropic viral infections
por: Swingler, Michael, et al.
Publicado: (2023)

In depth characterization of midbrain organoids derived from wild type iPSC lines
por: Pavlinov, Ivan, et al.
Publicado: (2023)

Development of lacrimal gland organoids from iPSC derived multizonal ocular cells
por: Asal, Melis, et al.
Publicado: (2023)

The Generation of Human iPSC Lines from Three Individuals with Dravet Syndrome and Characterization of Neural Differentiation Markers in iPSC-Derived Ventral Forebrain Organoid Model
por: Zayat, Valery, et al.
Publicado: (2023)

Application of an iPSC‐Derived Organoid Model for Localized Scleroderma Therapy (Adv. Sci. 16/2022)
por: Ma, Jie, et al.
Publicado: (2022)

Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids
por: Zhang, Ran-Ran, et al.
Publicado: (2018)

Modeling and Rescue of RP2 Retinitis Pigmentosa Using iPSC-Derived Retinal Organoids
por: Lane, Amelia, et al.
Publicado: (2020)

Tropism of AAV Vectors in Photoreceptor-Like Cells of Human iPSC-Derived Retinal Organoids
por: McClements, Michelle E., et al.
Publicado: (2022)

Enhanced Microvasculature Formation and Patterning in iPSC–Derived Kidney Organoids Cultured in Physiological Hypoxia
por: Schumacher, Anika, et al.
Publicado: (2022)

Bilirubin-Induced Neurological Damage: Current and Emerging iPSC-Derived Brain Organoid Models
por: Pranty, Abida Islam, et al.
Publicado: (2022)

Whole-exome Sequencing and an iPSC-Derived Cardiomyocyte Model Provides a Powerful Platform for Gene Discovery in Left Ventricular Hypertrophy
por: Zhi, D., et al.
Publicado: (2012)

Downregulation of neurodevelopmental gene expression in iPSC-derived cerebral organoids upon infection by human cytomegalovirus
por: O’Brien, Benjamin S., et al.
Publicado: (2022)

MEDB-22. iPSC-derived cerebellar organoid model for hereditary genetic predisposition in SHH-medulloblastoma
por: Manz, Frederik, et al.
Publicado: (2022)

Human iPSC-derived cerebral organoids model features of Leigh syndrome and reveal abnormal corticogenesis
por: Romero-Morales, Alejandra I., et al.
Publicado: (2022)

Modeling brain macrophage biology and neurodegenerative diseases using human iPSC-derived neuroimmune organoids
por: Cerneckis, Jonas, et al.
Publicado: (2023)

Human iPSC-Derived 3D Hepatic Organoids in a Miniaturized Dynamic Culture System
por: Calamaio, Serena, et al.
Publicado: (2023)

APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids
por: Zhao, Jing, et al.
Publicado: (2023)

Stabilized generation of human iPSC-derived liver organoids using a modified coating approach
por: Kamishibahara, Yu, et al.
Publicado: (2022)

Comparison of miRNA transcriptome of exosomes in three categories of somatic cells with derived iPSCs
por: Yu, Chunlai, et al.
Publicado: (2023)

Characterization and Transplantation of CD73-Positive Photoreceptors Isolated from Human iPSC-Derived Retinal Organoids
por: Gagliardi, Giuliana, et al.
Publicado: (2018)

APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids
por: Zhao, Jing, et al.
Publicado: (2020)

The proteomic architecture of schizophrenia iPSC-derived cerebral organoids reveals alterations in GWAS and neuronal development factors
por: Notaras, Michael, et al.
Publicado: (2021)

Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids
por: Zhao, Jing, et al.
Publicado: (2021)

Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis
por: Yucer, Nur, et al.
Publicado: (2021)

Single-cell multiomics reveals the complexity of TGFβ signalling to chromatin in iPSC-derived kidney organoids
por: Davis, Jessica L., et al.
Publicado: (2022)

iPSC-derived type IV collagen α5-expressing kidney organoids model Alport syndrome
por: Hirayama, Ryuichiro, et al.
Publicado: (2023)

Development of brain organoid technology derived from iPSC for the neurodegenerative disease modelling: a glance through
por: Jusop, Amirah Syamimi, et al.
Publicado: (2023)

Human iPSC-Derived Retinal Organoids and Retinal Pigment Epithelium for Novel Intronic RPGR Variant Assessment for Therapy Suitability
por: Chahine Karam, Fidelle, et al.
Publicado: (2022)

Banking on iPSC- Is it Doable and is it Worthwhile
por: Solomon, Susan, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_eqbl1cobr5af2ur6mi6atf7fb1