White Matter Hyperintensities Are No Major Confounder for Alzheimer’s Disease Cerebrospinal Fluid Biomarkers

BACKGROUND: The cerebrospinal fluid (CSF) biomarkers amyloid-β 1–42 (Aβ(42)), total and phosphorylated tau (t-tau, p-tau) are increasingly used to assist in the clinical diagnosis of Alzheimer’s disease (AD). However, CSF biomarker levels can be affected by confounding factors. OBJECTIVE: To investi...

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Detalles Bibliográficos
Autores principales: van Waalwijk van Doorn, Linda J.C., Ghafoorian, Mohsen, van Leijsen, Esther M.C., Claassen, Jurgen A.H.R., Arighi, Andrea, Bozzali, Marco, Cannas, Jorge, Cavedo, Enrica, Eusebi, Paolo, Farotti, Lucia, Fenoglio, Chiara, Fortea, Juan, Frisoni, Giovanni B., Galimberti, Daniela, Greco, Viviana, Herukka, Sanna-Kaisa, Liu, Yawu, Lleó, Alberto, de Mendonça, Alexandre, Nobili, Flavio M., Parnetti, Lucilla, Picco, Agnese, Pikkarainen, Maria, Salvadori, Nicola, Scarpini, Elio, Soininen, Hilkka, Tarducci, Roberto, Urbani, Andrea, Vilaplana, Eduard, Meulenbroek, Olga, Platel, Bram, Verbeek, Marcel M., Kuiperij, H. Bea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902951/
https://www.ncbi.nlm.nih.gov/pubmed/33252070
http://dx.doi.org/10.3233/JAD-200496

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