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Porphyromonas Gingivalis May Seek the Alzheimer’s Disease Brain to Acquire Iron from Its Surplus
Iron accumulates in the brain of subjects with Alzheimer’s disease (AD). Here it promotes the aggregation of amyloid-β plaques in which it is abundant. Iron induces amyloid-β neurotoxicity by damaging free radicals and causing oxidative stress in brain areas with neurodegeneration. It can also bind...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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IOS Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903007/ https://www.ncbi.nlm.nih.gov/pubmed/33681719 http://dx.doi.org/10.3233/ADR-200272 |