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Safety and acceptability of clozapine and risperidone in progressive multiple sclerosis: a phase I, randomised, blinded, placebo-controlled trial
OBJECTIVE: Because clozapine and risperidone have been shown to reduce neuroinflammation in humans and mice, the Clozapine and Risperidone in Progressive Multiple Sclerosis (CRISP) trial was conducted to determine whether clozapine and risperidone are suitable for progressive multiple sclerosis (pMS...
Autores principales: | La Flamme, Anne C, Abernethy, David, Sim, Dalice, Goode, Liz, Lockhart, Michelle, Bourke, David, Milner, Imogen, Garrill, Toni-Marie, Joshi, Purwa, Watson, Eloise, Smyth, Duncan, Lance, Sean, Connor, Bronwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903182/ https://www.ncbi.nlm.nih.gov/pubmed/33681788 http://dx.doi.org/10.1136/bmjno-2020-000060 |
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