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SARS-CoV-2 Testing for Asymptomatic Patients with Cancer Prior and during Treatment: A Single Centre Experience

Patients with cancer are more vulnerable to severe COVID-19. As a result, routine SARS-CoV-2 testing of asymptomatic patients with cancer is recommended prior to treatment. However, there is limited evidence of its clinical usefulness. The objective of this study is to evaluate the value of routine...

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Autores principales: Meti, Nicholas, Tahmasebi, Houman, Leahey, Angela, Boudreau, Angela, Thawer, Alia, Stewart, Janice, Reason, Paige, Albright, Kirsty, Leis, Jerome A., Katz, Kevin, Cheung, Matthew C., Singh, Simron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903264/
https://www.ncbi.nlm.nih.gov/pubmed/33419159
http://dx.doi.org/10.3390/curroncol28010032
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author Meti, Nicholas
Tahmasebi, Houman
Leahey, Angela
Boudreau, Angela
Thawer, Alia
Stewart, Janice
Reason, Paige
Albright, Kirsty
Leis, Jerome A.
Katz, Kevin
Cheung, Matthew C.
Singh, Simron
author_facet Meti, Nicholas
Tahmasebi, Houman
Leahey, Angela
Boudreau, Angela
Thawer, Alia
Stewart, Janice
Reason, Paige
Albright, Kirsty
Leis, Jerome A.
Katz, Kevin
Cheung, Matthew C.
Singh, Simron
author_sort Meti, Nicholas
collection PubMed
description Patients with cancer are more vulnerable to severe COVID-19. As a result, routine SARS-CoV-2 testing of asymptomatic patients with cancer is recommended prior to treatment. However, there is limited evidence of its clinical usefulness. The objective of this study is to evaluate the value of routine testing of asymptomatic patients with cancer. Asymptomatic patients with cancer attending Odette Cancer Centre (Toronto, ON, Canada) were tested for SARS-CoV-2 prior to and during treatment cycles. Results were compared to positivity rates of SARS-CoV-2 locally and provincially. All 890 asymptomatic patients tested negative. Positivity rates in the province were 1.5%, in hospital were 1.0%, and among OCC’s symptomatic cancer patients were 0% over the study period. Given our findings and the low SARS-CoV-2 community positivity rates, we recommend a dynamic testing model of asymptomatic patients that triggers testing during increasing community positivity rates of SARS-CoV-2.
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spelling pubmed-79032642021-02-25 SARS-CoV-2 Testing for Asymptomatic Patients with Cancer Prior and during Treatment: A Single Centre Experience Meti, Nicholas Tahmasebi, Houman Leahey, Angela Boudreau, Angela Thawer, Alia Stewart, Janice Reason, Paige Albright, Kirsty Leis, Jerome A. Katz, Kevin Cheung, Matthew C. Singh, Simron Curr Oncol Communication Patients with cancer are more vulnerable to severe COVID-19. As a result, routine SARS-CoV-2 testing of asymptomatic patients with cancer is recommended prior to treatment. However, there is limited evidence of its clinical usefulness. The objective of this study is to evaluate the value of routine testing of asymptomatic patients with cancer. Asymptomatic patients with cancer attending Odette Cancer Centre (Toronto, ON, Canada) were tested for SARS-CoV-2 prior to and during treatment cycles. Results were compared to positivity rates of SARS-CoV-2 locally and provincially. All 890 asymptomatic patients tested negative. Positivity rates in the province were 1.5%, in hospital were 1.0%, and among OCC’s symptomatic cancer patients were 0% over the study period. Given our findings and the low SARS-CoV-2 community positivity rates, we recommend a dynamic testing model of asymptomatic patients that triggers testing during increasing community positivity rates of SARS-CoV-2. MDPI 2021-01-06 /pmc/articles/PMC7903264/ /pubmed/33419159 http://dx.doi.org/10.3390/curroncol28010032 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Meti, Nicholas
Tahmasebi, Houman
Leahey, Angela
Boudreau, Angela
Thawer, Alia
Stewart, Janice
Reason, Paige
Albright, Kirsty
Leis, Jerome A.
Katz, Kevin
Cheung, Matthew C.
Singh, Simron
SARS-CoV-2 Testing for Asymptomatic Patients with Cancer Prior and during Treatment: A Single Centre Experience
title SARS-CoV-2 Testing for Asymptomatic Patients with Cancer Prior and during Treatment: A Single Centre Experience
title_full SARS-CoV-2 Testing for Asymptomatic Patients with Cancer Prior and during Treatment: A Single Centre Experience
title_fullStr SARS-CoV-2 Testing for Asymptomatic Patients with Cancer Prior and during Treatment: A Single Centre Experience
title_full_unstemmed SARS-CoV-2 Testing for Asymptomatic Patients with Cancer Prior and during Treatment: A Single Centre Experience
title_short SARS-CoV-2 Testing for Asymptomatic Patients with Cancer Prior and during Treatment: A Single Centre Experience
title_sort sars-cov-2 testing for asymptomatic patients with cancer prior and during treatment: a single centre experience
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903264/
https://www.ncbi.nlm.nih.gov/pubmed/33419159
http://dx.doi.org/10.3390/curroncol28010032
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