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Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review

Implant-supported dentures are widely used in patients with defect or loss of dentition because these have higher chewing efficiency and do not damage the adjacent teeth compared with fixed or removable denture. An implant-supported denture carries the risk of failure in some systemic diseases, incl...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng, Zhang, Tianjia, Geng, Tengyu, Wang, Xudong, Lin, Kaili, Wang, Penglai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903335/
https://www.ncbi.nlm.nih.gov/pubmed/33644012
http://dx.doi.org/10.3389/fbioe.2021.591796
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author Zhang, Cheng
Zhang, Tianjia
Geng, Tengyu
Wang, Xudong
Lin, Kaili
Wang, Penglai
author_facet Zhang, Cheng
Zhang, Tianjia
Geng, Tengyu
Wang, Xudong
Lin, Kaili
Wang, Penglai
author_sort Zhang, Cheng
collection PubMed
description Implant-supported dentures are widely used in patients with defect or loss of dentition because these have higher chewing efficiency and do not damage the adjacent teeth compared with fixed or removable denture. An implant-supported denture carries the risk of failure in some systemic diseases, including osteoporosis, because of a non-ideal local microenvironment. Clinically common physical and chemical modifications are used to change the roughness of the implant surface to promote osseointegration, but they have limitations in promoting osteoinduction and inhibiting bone resorption. Recently, many researchers have focused on the study of bioactive modification of implants and have achieved promising results. Herein we have summarized the progress in bioactive modification strategy to promote osseointegration by regulating the local osteoporotic microenvironment.
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spelling pubmed-79033352021-02-25 Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review Zhang, Cheng Zhang, Tianjia Geng, Tengyu Wang, Xudong Lin, Kaili Wang, Penglai Front Bioeng Biotechnol Bioengineering and Biotechnology Implant-supported dentures are widely used in patients with defect or loss of dentition because these have higher chewing efficiency and do not damage the adjacent teeth compared with fixed or removable denture. An implant-supported denture carries the risk of failure in some systemic diseases, including osteoporosis, because of a non-ideal local microenvironment. Clinically common physical and chemical modifications are used to change the roughness of the implant surface to promote osseointegration, but they have limitations in promoting osteoinduction and inhibiting bone resorption. Recently, many researchers have focused on the study of bioactive modification of implants and have achieved promising results. Herein we have summarized the progress in bioactive modification strategy to promote osseointegration by regulating the local osteoporotic microenvironment. Frontiers Media S.A. 2021-02-09 /pmc/articles/PMC7903335/ /pubmed/33644012 http://dx.doi.org/10.3389/fbioe.2021.591796 Text en Copyright © Zhang, Zhang, Geng, Wang, Lin and Wang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Zhang, Cheng
Zhang, Tianjia
Geng, Tengyu
Wang, Xudong
Lin, Kaili
Wang, Penglai
Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review
title Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review
title_full Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review
title_fullStr Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review
title_full_unstemmed Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review
title_short Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review
title_sort dental implants loaded with bioactive agents promote osseointegration in osteoporosis: a review
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903335/
https://www.ncbi.nlm.nih.gov/pubmed/33644012
http://dx.doi.org/10.3389/fbioe.2021.591796
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