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Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review
Implant-supported dentures are widely used in patients with defect or loss of dentition because these have higher chewing efficiency and do not damage the adjacent teeth compared with fixed or removable denture. An implant-supported denture carries the risk of failure in some systemic diseases, incl...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903335/ https://www.ncbi.nlm.nih.gov/pubmed/33644012 http://dx.doi.org/10.3389/fbioe.2021.591796 |
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author | Zhang, Cheng Zhang, Tianjia Geng, Tengyu Wang, Xudong Lin, Kaili Wang, Penglai |
author_facet | Zhang, Cheng Zhang, Tianjia Geng, Tengyu Wang, Xudong Lin, Kaili Wang, Penglai |
author_sort | Zhang, Cheng |
collection | PubMed |
description | Implant-supported dentures are widely used in patients with defect or loss of dentition because these have higher chewing efficiency and do not damage the adjacent teeth compared with fixed or removable denture. An implant-supported denture carries the risk of failure in some systemic diseases, including osteoporosis, because of a non-ideal local microenvironment. Clinically common physical and chemical modifications are used to change the roughness of the implant surface to promote osseointegration, but they have limitations in promoting osteoinduction and inhibiting bone resorption. Recently, many researchers have focused on the study of bioactive modification of implants and have achieved promising results. Herein we have summarized the progress in bioactive modification strategy to promote osseointegration by regulating the local osteoporotic microenvironment. |
format | Online Article Text |
id | pubmed-7903335 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79033352021-02-25 Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review Zhang, Cheng Zhang, Tianjia Geng, Tengyu Wang, Xudong Lin, Kaili Wang, Penglai Front Bioeng Biotechnol Bioengineering and Biotechnology Implant-supported dentures are widely used in patients with defect or loss of dentition because these have higher chewing efficiency and do not damage the adjacent teeth compared with fixed or removable denture. An implant-supported denture carries the risk of failure in some systemic diseases, including osteoporosis, because of a non-ideal local microenvironment. Clinically common physical and chemical modifications are used to change the roughness of the implant surface to promote osseointegration, but they have limitations in promoting osteoinduction and inhibiting bone resorption. Recently, many researchers have focused on the study of bioactive modification of implants and have achieved promising results. Herein we have summarized the progress in bioactive modification strategy to promote osseointegration by regulating the local osteoporotic microenvironment. Frontiers Media S.A. 2021-02-09 /pmc/articles/PMC7903335/ /pubmed/33644012 http://dx.doi.org/10.3389/fbioe.2021.591796 Text en Copyright © Zhang, Zhang, Geng, Wang, Lin and Wang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Zhang, Cheng Zhang, Tianjia Geng, Tengyu Wang, Xudong Lin, Kaili Wang, Penglai Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
title | Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
title_full | Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
title_fullStr | Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
title_full_unstemmed | Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
title_short | Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
title_sort | dental implants loaded with bioactive agents promote osseointegration in osteoporosis: a review |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903335/ https://www.ncbi.nlm.nih.gov/pubmed/33644012 http://dx.doi.org/10.3389/fbioe.2021.591796 |
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