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Chimeric antigen receptor-natural killer cells: Novel insight into immunotherapy for solid tumors (Review)

The chimeric antigen receptor (CAR) is an artificially modified fusion protein consisting of an extracellular antigen-binding domain, transmembrane domain and intracellular signalling domain. CAR-T therapy has demonstrated remarkable clinical efficacy in hematological malignancies. However, cytokine...

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Detalles Bibliográficos
Autores principales: Peng, Xiaobo, Chen, Ling, Chen, Longpei, Wang, Bin, Wang, Yiran, Zhan, Xianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903426/
https://www.ncbi.nlm.nih.gov/pubmed/33732313
http://dx.doi.org/10.3892/etm.2021.9771