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Synthesis of an Hsp70 inhibitor and its assessment of lysosomal membrane permeabilization
Hsp70 inhibitors have great potential as chemical probes and anticancer agents. Thus, it is important to elucidate their modes of action on cancer cell death. This protocol describes a step-by-step process for the synthesis of apoptozole as an inhibitor of Hsp70, analysis of internalization of apopt...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903460/ https://www.ncbi.nlm.nih.gov/pubmed/33665629 http://dx.doi.org/10.1016/j.xpro.2021.100349 |