Functional inhibition of Oct leads to HNF4α upregulation

Organic cation transporters (human, OCT; mouse, Oct) are responsible for the intracellular uptake and detoxification of a broad spectrum of endogenous and exogenous substrates. The OCT1 gene SLC22A1 (human; mouse, Scl22a1) is transactivated by hepatocyte nuclear factor 4α (human, HNF4α; mouse, Hnf4α...

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Detalles Bibliográficos
Autores principales: Vollmar, Johanna, Kim, Yong Ook, Marquardt, Jens Uwe, Galle, Peter R., Schuppan, Detlef, Zimmermann, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903485/
https://www.ncbi.nlm.nih.gov/pubmed/33732322
http://dx.doi.org/10.3892/etm.2021.9780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903485/
https://www.ncbi.nlm.nih.gov/pubmed/33732322
http://dx.doi.org/10.3892/etm.2021.9780

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