Cargando…

A critical role of AREG for bleomycin-induced skin fibrosis

We report our discovery of an important player in the development of skin fibrosis, a hallmark of scleroderma. Scleroderma is a fibrotic disease, affecting 70,000 to 150,000 Americans. Fibrosis is a pathological wound healing process that produces an excessive extracellular matrix to interfere with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Mary Yinghua, Fang, Shuyi, Gao, Hongyu, Zhang, Xiaoli, Gu, Dongsheng, Liu, Yunlong, Wan, Jun, Xie, Jingwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903615/ https://www.ncbi.nlm.nih.gov/pubmed/33622407 http://dx.doi.org/10.1186/s13578-021-00553-0

Ejemplares similares

Cell Population Analyses During Skin Carcinogenesis
por: Gu, Dongsheng, et al.
Publicado: (2013)

Loss of KIBRA function activates EGFR signaling by inducing AREG
por: Mussell, Ashley L., et al.
Publicado: (2018)

Expression and Clinical Significance of YAP, TAZ, and AREG in Hepatocellular Carcinoma
por: Han, Su-xia, et al.
Publicado: (2014)

Imrecoxib attenuates bleomycin-induced pulmonary fibrosis in mice
por: Miao, Yang, et al.
Publicado: (2023)

Antifibrotic Mechanism of Piceatannol in Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Sheng, Hanjing, et al.
Publicado: (2022)

Genome Sequence of the Enterohemorrhagic Escherichia coli Bacteriophage UFV-AREG1
por: Lopez, Maryoris E. Soto, et al.
Publicado: (2016)

Significance of Amphiregulin (AREG) for the Outcome of Low and High Grade Astrocytoma Patients
por: Steponaitis, Giedrius, et al.
Publicado: (2019)

CCN1 expression by fibroblasts is required for bleomycin-induced skin fibrosis
por: Quesnel, Katherine, et al.
Publicado: (2019)

Activation of the Hedgehog signaling pathway leads to fibrosis in aortic valves
por: Gu, Dongsheng, et al.
Publicado: (2023)

Vagotomy attenuates bleomycin-induced pulmonary fibrosis in mice
por: Song, Nana, et al.
Publicado: (2015)

Regulation of pancreatic cancer metastasis through the Gli2-YAP1 axis via regulation of anoikis
por: Yu, Beiqin, et al.
Publicado: (2022)

Simultaneous Inhibition of MEK and Hh Signaling Reduces Pancreatic Cancer Metastasis
por: Gu, Dongsheng, et al.
Publicado: (2018)

Rationale, design and objectives of ARegPKD, a European ARPKD registry study
por: Ebner, Kathrin, et al.
Publicado: (2015)

BMP-7 Does Not Protect against Bleomycin-Induced Lung or Skin Fibrosis
por: Murray, Lynne A., et al.
Publicado: (2008)

mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis
por: McCann, Matthew R, et al.
Publicado: (2011)

Mirodenafil ameliorates skin fibrosis in bleomycin-induced mouse model of systemic sclerosis
por: Roh, Jong Seong, et al.
Publicado: (2021)

Laser Therapy Changes the Expression of Matrix Metalloproteinases in Bleomycin-Induced Skin Fibrosis
por: Soboleva, Anna G., et al.
Publicado: (2023)

Preventive effects of vitamin D treatment on bleomycin-induced pulmonary fibrosis
por: Zhang, Zongmei, et al.
Publicado: (2015)

M6AREG: m(6)A-centered regulation of disease development and drug response
por: Liu, Shuiping, et al.
Publicado: (2022)

Bleomycin induced hyperpigmentation of skin
por: Mishra, Kundan, et al.
Publicado: (2018)

The role of GLI-SOX2 signaling axis for gemcitabine resistance in pancreatic cancer
por: Jia, Yanfei, et al.
Publicado: (2018)

Recent Progress of the ARegPKD Registry Study on Autosomal Recessive Polycystic Kidney Disease
por: Ebner, Kathrin, et al.
Publicado: (2017)

Correction: mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis
por: McCann, Matthew R, et al.
Publicado: (2011)

Butyrate Improves Skin/Lung Fibrosis and Intestinal Dysbiosis in Bleomycin-Induced Mouse Models
por: Park, Hee Jin, et al.
Publicado: (2021)

A cysteine proteinase inhibitor ALLN alleviates bleomycin-induced skin and lung fibrosis
por: Kasamatsu, Hiroshi, et al.
Publicado: (2023)

Immune Mechanisms of Pulmonary Fibrosis with Bleomycin
por: Ishida, Yuko, et al.
Publicado: (2023)

GLI1-mediated regulation of side population is responsible for drug resistance in gastric cancer
por: Yu, Beiqin, et al.
Publicado: (2017)

Non-Canonical Hh Signaling in Cancer—Current Understanding and Future Directions
por: Gu, Dongsheng, et al.
Publicado: (2015)

Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer
por: Lee, Michael S, et al.
Publicado: (2016)

Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG
por: Cheng, Yaojia, et al.
Publicado: (2020)

Combined effect of genetic background and gender in a mouse model of bleomycin-induced skin fibrosis
por: Ruzehaji, Nadira, et al.
Publicado: (2015)

The role of GLI1 for 5-Fu resistance in colorectal cancer
por: Zhang, Lining, et al.
Publicado: (2017)

Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Bilobalide
por: Zhang, Xingcai, et al.
Publicado: (2023)

Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice
por: Huang, Jizhen, et al.
Publicado: (2020)

Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Han, Yuanyuan, et al.
Publicado: (2021)

Megakaryocytes participate in the occurrence of bleomycin-induced pulmonary fibrosis
por: Zhou, Yan, et al.
Publicado: (2019)

Antifibrotic Mechanism of Cinobufagin in Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Li, Xiaohe, et al.
Publicado: (2019)

Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice
por: Liu, Wei, et al.
Publicado: (2013)

Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis in rats
por: HE, HUANYU, et al.
Publicado: (2015)

Sodium Houttuyfonate Inhibits Bleomycin Induced Pulmonary Fibrosis in Mice
por: Shen, Yun-hui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dq6hrkp8kdrlppnok2ojefittl