Identification of novel, clonally stable, somatic mutations targeting transcription factors PAX5 and NKX2-3, the epigenetic regulator LRIF1, and BRAF in a case of atypical B-cell chronic lymphocytic leukemia harboring a t(14;18)(q32;q21)

Diagnosis of B-cell chronic lymphocytic leukemia (B-CLL) is usually straightforward, involving clinical, immunophenotypic (Matutes score), and (immuno)genetic analyses (to refine patient prognosis for treatment). CLL cases with atypical presentation (e.g., Matutes ≤ 3) are also encountered, and for...

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Detalles Bibliográficos
Autores principales: Burlet, Bénédicte, Ramla, Selim, Fournier, Cyril, Abrey-Recalde, Maria Jimena, Sauter, Camille, Chrétien, Marie-Lorraine, Rossi, Cédric, Duffourd, Yannis, Ragot, Sylviane, Buriller, Céline, Tournier, Benjamin, Chapusot, Caroline, Nadal, Nathalie, Racine, Jessica, Guy, Julien, Bailly, François, Martin, Laurent, Casasnovas, Olivier, Bastie, Jean-Noël, Caillot, Denis, Albuisson, Juliette, Broccardo, Cyril, Thieblemont, Catherine, Delva, Laurent, Maynadié, Marc, Aucagne, Romain, Callanan, Mary B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Rapid Cancer Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903887/
https://www.ncbi.nlm.nih.gov/pubmed/33608382
http://dx.doi.org/10.1101/mcs.a005934

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