A muscle growth-promoting treatment based on the attenuation of activin/myostatin signalling results in long-term testicular abnormalities

Activin/myostatin signalling acts to induce skeletal muscle atrophy in adult mammals by inhibiting protein synthesis as well as promoting protein and organelle turnover. Numerous strategies have been successfully developed to attenuate the signalling properties of these molecules, which result in au...

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Detalles Bibliográficos
Autores principales: Vaughan, Danielle, Mitchell, Robert, Kretz, Oliver, Chambers, David, Lalowski, Maciej, Amthor, Helge, Ritvos, Olli, Pasternack, Arja, Matsakas, Antonios, Vaiyapuri, Sakthivel, Huber, Tobias B., Denecke, Bernd, Mukherjee, Abir, Widera, Darius, Patel, Ketan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903914/
https://www.ncbi.nlm.nih.gov/pubmed/33408083
http://dx.doi.org/10.1242/dmm.047555

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