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Signatures of neutral evolution in exponentially growing tumors: A theoretical perspective
Recent work of Sottoriva, Graham, and collaborators have led to the controversial claim that exponentially growing tumors have a site frequency spectrum that follows the 1/f law consistent with neutral evolution. This conclusion has been criticized based on data quality issues, statistical considera...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904140/ https://www.ncbi.nlm.nih.gov/pubmed/33571199 http://dx.doi.org/10.1371/journal.pcbi.1008701 |