Cargando…

Clinical outcomes of proximal gastrectomy for gastric cancer: A comparison between the double-flap technique and jejunal interposition

BACKGROUND: The optimal reconstruction method after proximal gastrectomy (PG) has been debatable. Recent reports have shown that the double-flap technique (DFT) provides good outcomes in terms of postoperative nutritional status and quality of life. However, no study has compared the clinical outcom...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumamoto, Tsutomu, Sasako, Mitsuru, Ishida, Yoshinori, Kurahashi, Yasunori, Shinohara, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904176/
https://www.ncbi.nlm.nih.gov/pubmed/33626086
http://dx.doi.org/10.1371/journal.pone.0247636
_version_ 1783654876632317952
author Kumamoto, Tsutomu
Sasako, Mitsuru
Ishida, Yoshinori
Kurahashi, Yasunori
Shinohara, Hisashi
author_facet Kumamoto, Tsutomu
Sasako, Mitsuru
Ishida, Yoshinori
Kurahashi, Yasunori
Shinohara, Hisashi
author_sort Kumamoto, Tsutomu
collection PubMed
description BACKGROUND: The optimal reconstruction method after proximal gastrectomy (PG) has been debatable. Recent reports have shown that the double-flap technique (DFT) provides good outcomes in terms of postoperative nutritional status and quality of life. However, no study has compared the clinical outcomes of the DFT with other reconstruction methods. Here, we evaluated and compared the clinical outcomes between the DFT and jejunal interposition (JI) after PG for gastric cancer. MATERIALS AND METHODS: The medical records of 34 consecutive patients who had undergone PG for upper third gastric cancer between January 2011 and October 2016 were reviewed retrospectively. The main factors investigated were surgical outcomes, postoperative nutritional status, symptoms, and endoscopic findings 1 year after surgery. RESULTS: Thirty-four patients were enrolled (DFT, 14; JI, 20). The operation time was similar between the two techniques (228 and 246 minutes for DFT and JI, respectively, P = 0.377), as were the rates of anastomotic complications (7% and 0% for DFT and JI, respectively, P = 0.412). Body weight loss was significantly lower in the DFT group than in the JI group (-8.1% vs -16.1%, P = 0.001). Total protein and albumin levels were higher in the DFT group than in the JI group (0% vs -2.9%, P = 0.053, and -0.3% vs -6.1%, P = 0.077, respectively). One patient in the DFT group and no patients in the JI group experienced reflux esophagitis (≥ grade B) (P = 0.393). Anastomotic strictures were not observed as postoperative complications in either group. CONCLUSIONS: Surgical outcomes revealed that the DFT was safe and feasible, similar to JI. In terms of controlling postoperative body weight loss, the DFT is a better reconstruction technique than JI after PG.
format Online
Article
Text
id pubmed-7904176
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-79041762021-03-02 Clinical outcomes of proximal gastrectomy for gastric cancer: A comparison between the double-flap technique and jejunal interposition Kumamoto, Tsutomu Sasako, Mitsuru Ishida, Yoshinori Kurahashi, Yasunori Shinohara, Hisashi PLoS One Research Article BACKGROUND: The optimal reconstruction method after proximal gastrectomy (PG) has been debatable. Recent reports have shown that the double-flap technique (DFT) provides good outcomes in terms of postoperative nutritional status and quality of life. However, no study has compared the clinical outcomes of the DFT with other reconstruction methods. Here, we evaluated and compared the clinical outcomes between the DFT and jejunal interposition (JI) after PG for gastric cancer. MATERIALS AND METHODS: The medical records of 34 consecutive patients who had undergone PG for upper third gastric cancer between January 2011 and October 2016 were reviewed retrospectively. The main factors investigated were surgical outcomes, postoperative nutritional status, symptoms, and endoscopic findings 1 year after surgery. RESULTS: Thirty-four patients were enrolled (DFT, 14; JI, 20). The operation time was similar between the two techniques (228 and 246 minutes for DFT and JI, respectively, P = 0.377), as were the rates of anastomotic complications (7% and 0% for DFT and JI, respectively, P = 0.412). Body weight loss was significantly lower in the DFT group than in the JI group (-8.1% vs -16.1%, P = 0.001). Total protein and albumin levels were higher in the DFT group than in the JI group (0% vs -2.9%, P = 0.053, and -0.3% vs -6.1%, P = 0.077, respectively). One patient in the DFT group and no patients in the JI group experienced reflux esophagitis (≥ grade B) (P = 0.393). Anastomotic strictures were not observed as postoperative complications in either group. CONCLUSIONS: Surgical outcomes revealed that the DFT was safe and feasible, similar to JI. In terms of controlling postoperative body weight loss, the DFT is a better reconstruction technique than JI after PG. Public Library of Science 2021-02-24 /pmc/articles/PMC7904176/ /pubmed/33626086 http://dx.doi.org/10.1371/journal.pone.0247636 Text en © 2021 Kumamoto et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Kumamoto, Tsutomu
Sasako, Mitsuru
Ishida, Yoshinori
Kurahashi, Yasunori
Shinohara, Hisashi
Clinical outcomes of proximal gastrectomy for gastric cancer: A comparison between the double-flap technique and jejunal interposition
title Clinical outcomes of proximal gastrectomy for gastric cancer: A comparison between the double-flap technique and jejunal interposition
title_full Clinical outcomes of proximal gastrectomy for gastric cancer: A comparison between the double-flap technique and jejunal interposition
title_fullStr Clinical outcomes of proximal gastrectomy for gastric cancer: A comparison between the double-flap technique and jejunal interposition
title_full_unstemmed Clinical outcomes of proximal gastrectomy for gastric cancer: A comparison between the double-flap technique and jejunal interposition
title_short Clinical outcomes of proximal gastrectomy for gastric cancer: A comparison between the double-flap technique and jejunal interposition
title_sort clinical outcomes of proximal gastrectomy for gastric cancer: a comparison between the double-flap technique and jejunal interposition
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904176/
https://www.ncbi.nlm.nih.gov/pubmed/33626086
http://dx.doi.org/10.1371/journal.pone.0247636
work_keys_str_mv AT kumamototsutomu clinicaloutcomesofproximalgastrectomyforgastriccanceracomparisonbetweenthedoubleflaptechniqueandjejunalinterposition
AT sasakomitsuru clinicaloutcomesofproximalgastrectomyforgastriccanceracomparisonbetweenthedoubleflaptechniqueandjejunalinterposition
AT ishidayoshinori clinicaloutcomesofproximalgastrectomyforgastriccanceracomparisonbetweenthedoubleflaptechniqueandjejunalinterposition
AT kurahashiyasunori clinicaloutcomesofproximalgastrectomyforgastriccanceracomparisonbetweenthedoubleflaptechniqueandjejunalinterposition
AT shinoharahisashi clinicaloutcomesofproximalgastrectomyforgastriccanceracomparisonbetweenthedoubleflaptechniqueandjejunalinterposition