Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission

Posttranslational modifications, such as SUMOylation, play specific roles in the life cycle of invading pathogens. However, the effect of SUMOylation on the adaptation, pathogenesis, and transmission of influenza A virus (IAV) remains largely unknown. Here, we found that a conserved lysine residue a...

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Detalles Bibliográficos
Autores principales: Li, Junping, Liang, Libin, Jiang, Li, Wang, Qian, Wen, Xia, Zhao, Yuhui, Cui, Pengfei, Zhang, Yaping, Wang, Guangwen, Li, Qibing, Deng, Guohua, Shi, Jianzhong, Tian, Guobin, Zeng, Xianying, Jiang, Yongping, Liu, Liling, Chen, Hualan, Li, Chengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904188/
https://www.ncbi.nlm.nih.gov/pubmed/33571308
http://dx.doi.org/10.1371/journal.ppat.1009336

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