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When to wake up? The optimal waking-up strategies for starvation-induced persistence
Prolonged lag time can be induced by starvation contributing to the antibiotic tolerance of bacteria. We analyze the optimal lag time to survive and grow the iterative and stochastic application of antibiotics. A simple model shows that the optimal lag time can exhibit a discontinuous transition whe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904209/ https://www.ncbi.nlm.nih.gov/pubmed/33571191 http://dx.doi.org/10.1371/journal.pcbi.1008655 |