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Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters

SARS-CoV-2 infection results in viral burden in the respiratory tract, enabling transmission and leading to substantial lung pathology. The 1212C2 fully human monoclonal antibody was derived from an IgM memory B cell of a COVID-19 patient, has high affinity for the Spike protein receptor binding dom...

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Detalles Bibliográficos
Autores principales:	Piepenbrink, Michael S., Park, Jun-Gyu, Oladunni, Fatai S., Deshpande, Ashlesha, Basu, Madhubanti, Sarkar, Sanghita, Loos, Andreas, Woo, Jennifer, Lovalenti, Phillip, Sloan, Derek, Ye, Chengjin, Chiem, Kevin, Bates, Christopher W., Burch, Reuben E., Erdmann, Nathaniel B., Goepfert, Paul A., Truong, Vu L., Walter, Mark R., Martinez-Sobrido, Luis, Kobie, James J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904445/ https://www.ncbi.nlm.nih.gov/pubmed/33649747 http://dx.doi.org/10.1016/j.xcrm.2021.100218

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