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Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by a burst in the upper respiratory portal for high transmissibility. To determine human neutralizing antibodies (HuNAbs) for entry protection, we tested three potent HuNAbs (IC(50) range, 0.0007–0.35 μg/mL) against live S...

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Detalles Bibliográficos
Autores principales: Zhou, Dongyan, Chan, Jasper Fuk-Woo, Zhou, Biao, Zhou, Runhong, Li, Shuang, Shan, Sisi, Liu, Li, Zhang, Anna Jinxia, Chen, Serena J., Chan, Chris Chung-Sing, Xu, Haoran, Poon, Vincent Kwok-Man, Yuan, Shuofeng, Li, Cun, Chik, Kenn Ka-Heng, Chan, Chris Chun-Yiu, Cao, Jianli, Chan, Chun-Yin, Kwan, Ka-Yi, Du, Zhenglong, Lau, Thomas Tsz-Kan, Zhang, Qi, Zhou, Jie, To, Kelvin Kai-Wang, Zhang, Linqi, Ho, David D., Yuen, Kwok-Yung, Chen, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904446/
https://www.ncbi.nlm.nih.gov/pubmed/33657424
http://dx.doi.org/10.1016/j.chom.2021.02.019