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Assessment of cochlear toxicity in response to chronic 3,3′-iminodipropionitrile in mice reveals early and reversible functional loss that precedes overt histopathology

The peripheral auditory and vestibular systems rely on sensorineural structures that are vulnerable to ototoxic agents that cause hearing loss and/or equilibrium deficits. Although attention has focused on hair cell loss as the primary pathology underlying ototoxicity, evidence from the peripheral v...

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Detalles Bibliográficos
Autores principales: Greguske, Erin A., Llorens, Jordi, Pyott, Sonja J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904549/
https://www.ncbi.nlm.nih.gov/pubmed/33495873
http://dx.doi.org/10.1007/s00204-020-02962-5